Frontiers in Medical Science Research, 2019, 1(4); doi: 10.25236/FMSR.2019.010411.
Huiwen Kan, Xiaojing Shi, Qiuning Liu, Yanyan Bao, Yiming Chen, Jin Wang**, Zhenqiu Gao*
School of Pharmacy, Yancheng Teachers University, Xiwang Road, Yancheng 224007, China
*Corresponding Author
Bacterial hulls are used as bacterial shells that do not cover any nucleic acid cost and nucleus, especially in recent years. Studies on the surface of BGs have confirmed that many intact natural immune pattern recognition receptor agonists can be retained as immunological adjuvants. The resulting immune or non-immune secreted cytokines achieve effective activation of the adaptive immune response. This study will summarize the preparation technology of bacterial hulls, and analyze the mechanism of action as an immunoadjuvant, explore its application potential, and provide reference for similar research.
Bacterial capsid; Immune adjuvant; Feasibility
Huiwen Kan, Xiaojing Shi, Qiuning Liu, Yanyan Bao, Yiming Chen, Jin Wang, Zhenqiu Gao. Feasibility Study of Bacterial Hull as Immunological Adjuvant. Frontiers in Medical Science Research (2019) Vol. 1 Issue 4: 62-66. https://doi.org/10.25236/FMSR.2019.010411.
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