Irritable bowel syndrome (IBS) is one of the common diseases and frequently-occurring diseases of digestive system. Its clinical manifestations are mainly characterized by abdominal pain and changes in bowel habits. And it is difficult to cure it. The mainstays of treatments include diet, exercise, symptomatic treatment drugs and psychological intervention. These methods have good therapeutic effect but easy recurrence. Traditional Chinese medicine (TCM) emphasizes syndrome differentiation and treatment based on the etiology and pathogenesis, with good curative effect and limited side effects, so it has significant advantages in clinical practice. Understanding the signaling pathways associated with IBS is important for studying the pathogenesis of IBS in the future and for finding potential therapeutic targets. Taking the pathogenesis of irritable bowel syndrome as a starting point, this review introduces the modulation of IBS-related signalling pathways by TCM, aiming to provide in-depth studies on TCM treatment of IBS and inspire new research ideas.

Wang Yi, Song Jian. Review on Research Progress of Irritable Bowel Syndrome with Traditional Chinese Medicine Based on Signaling Pathways. Academic Journal of Medicine & Health Sciences (2023) Vol. 4, Issue 8: 20-25. https://doi.org/10.25236/AJMHS.2023.040804.

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