This article summarizes Director Ruixia Pei's clinical experience on new-onset type 2 diabetes mellitus, the characteristics of prescription and medication, and analyzes the cases by collecting and organizing typical cases. DirectorRuixia Pei believes that new-onset type 2 diabetes mellitus should be categorized as "thirst-quenching disease", and that the basic mechanism of new-onset type 2 diabetes mellitus is liver dysregulation and qi disorder. The essence of disease is deficiency syndrome, in which Yin deficiency is the essence and dry heat is the representation. In the process of treatment, nourishing yin and clearing heat throughout the process, and then take into account the evidence to dispel the pathogenic disease, and simultaneous treatment of both symptoms and root causes. The attached typical medical record is based on solid evidence, identified as yin deficiency and internal dryness, and the treatment is to regulate fluid, nourish yin and clear heat, together with lifestyle adjustments, to obtain satisfactory results. DirectorRuixia Pei attaches importance to clinical diagnosis and treatment of new-onset type 2 diabetes mellitus by using the "Harmony Method", which emphasizes the root of yin deficiency and takes into account the symptoms and realities of the disease, and the clinical efficacy is very good, which is worthy of popularization and study.

Xinyue Xu, Ruixia Pei. Director Ruixia Pei’s Experience in Identifying and Treating New Onset Type 2 Diabetes with the "Harmony Method". Frontiers in Medical Science Research (2023) Vol. 5, Issue 9: 86-92. https://doi.org/10.25236/FMSR.2023.050916.

[1] Chinese Diabetes Society, Zhu Dalong. Guideline for the prevention and treatment of type 2 diabetes mellitus in China(2020 edition) [J]. Chinese Journal of Diabetes Mellitus, 2021, 13(4):315-409.

[2] Gao Jing, Duan Chang, Li Lijuan. The Pathogenesis Mechanisms of Type 2 Diabetes Mellitus [J]. Medical Recapitulate 2015, 21(21):3935-3938.

[3] Liu Wei, Huang Fei, Lu Erli, Wu Yi. Discussion on the Early Prevention and Treatment of Type 2 Diabetes Based on the Chinese Medicine Therapy of “Purification and Purgation” [J]. Jiangsu Journal of Traditional Chinese Medicine. 2022, 54(11):47-49.

[4] Chen Xiaohong, Wang Yongfa, Li Yajing. Study on Relationship between TCM Syndrome and Relevant Objective Indicators in Newly Diagnosed Type 2 Diabetes [J]. Research of Integrated Traditional Chinese and Western Medicine. 2022, 14(4):221-224+233.

[5] Pang Guoming, Ni Qing, Zhang Fang. Guideline for Diagnosis and Treatment of Type Ⅱ Diabetes based on Syndrome Differentiation Combining with Disease Differentiation [J]. Journal of Traditional Chinese Medicine2021, 62(4):361-368.

[6] Wang Jinmei, Guo Junjie. Research progress of insulin resistance in type 2 diabetes treated with traditional Chinese medicine [J]. World Journal of Integrated Traditional and Western Medicine, 2017, 12(11): 1624-1628.

[7] Meng Xiangyun, Guo Shuming, Yang Lixia. Effect of Traditional Chinese Medicine Polysaccharides in Resisting Type 2 Diabetes Insulin [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2017, 23(8):220-225.

[8] Tong Xiaolin, Liu Ximing, Wei Junping, Ni Qing, Gao Qijian. Guidelines for prevention and treatment of diabetes in traditional Chinese Medicine [J]. Chinese Medicine Modern Distance Education of China, 2011, 9(4):148-151.

[9] Gao Huijuan, Feng Xingzhong. Feng Xingzhong's experience in treating diabetes mellitus from the liver [J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2016, 31(10):4066-4068.

[10] Gai Xiaohong, Liu Suxiang, Ren Tao, Liu Yi, Tian Chengwang. Research progress on chemical constituents of Coptidis Rhizoma and its pharmacological activities [J]. Chinese Traditional and Herbal Drugs, 2018, 49(20):4919-4927.

[11] Zhang Yanli, Wang Cong, Zhu Leilei, Su Chengfu, Shen Jiduo. Research Progress in Pharmacological Action of Baicalin [J]. Henan Traditional Chinese Medicine, 2019, 39(9):1450-1454.

[12] Weng Lili, Chen Li, Su Ying, Xu Tianyang. Chemical compositionand pharmacological action of Rhizoma Anemarrhenae [J]. Jilin Journal of Chinese Medicine, 2018, 38(1):90-92.

[13] Zhai Chunmei, Meng Xiangying, Fu Jingju, Qin Zhen, Meng Yonghai. Research Progress of Peony Bark in Modern Pharmacy[J]. Information on Traditional Chinese Medicine, 2020, 37(1): 109-114.

[14] Yuan Yuan. Research Progress of Lycii Cortex Chemical Composition, Measuring Content and Pharmacological Effect[J]. Clinical Journal of Traditional Chinese Medicine, 2018, 30(11): 2131-2134.