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Frontiers in Medical Science Research, 2023, 5(11); doi: 10.25236/FMSR.2023.051115.

Treatment of Bone Hyperplasia from the Perspective of Spleen and Kidney with Atractylodes Macrocephala as the Main Method


Pengzhang Yan1, Yingang Li2

Corresponding Author:
Yingang Li

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China


Bone hyperplasia is a degenerative disease that is inevitable during the aging process of the human body, with the continuous thickening of bone joints and their soft tissues. Pressing on other tissues causes pain and numbness. With the development of modern medical research, it has been found that " Atractylodes macrocephala " has many functions such as anti-inflammatory, anti-aging, and improving immune function. This article mainly discusses the treatment of bone hyperplasia based on "cultivating soil to make water" and" Atractylodes macrocephala", providing a theoretical basis for clinical treatment.


Soil cultivation for water; Atractylodes macrocephala; Bone hyperplasia; The spleen and kidney

Cite This Paper

Pengzhang Yan, Yingang Li. Treatment of Bone Hyperplasia from the Perspective of Spleen and Kidney with Atractylodes Macrocephala as the Main Method. Frontiers in Medical Science Research (2023) Vol. 5, Issue 11: 102-107. https://doi.org/10.25236/FMSR.2023.051115.


[1] Hong Qian. Kong Xiangying. Cheng Zongmin. Hu Jun (Lianyungang Hospital, Nanjing University of Traditional. Effect of Bushen Wenyang Zhitong Decoction Combined with Tuina on Lumbar Hyperosteogeny and Its Effect on Serum DKK1, SOST, TXB2 and 6-Keto-PGFlα [J]. Chinese Archives of Traditional Chinese Medicine, 2021, 39(8):162-165.  

[2] Li Xusheng. Observation on the curative effect of self-designed anti-bone hyperplasia decoction on 102 cases of bone hyperplasia[J]. Chinese Medicine information, 2010, 2(32):1. 

[3] Zhang Bo. Study on the application of white art in Treatise on Febrile Diseases [D]. Zhengzhou: Henan University of Traditional Chinese Medicine, 2017. 

[4] Zhang Xiaojuan, Zuo Dongdong. Recent progress in the study of chemical constituents and pharmacological effects of Rhizoma alba [J]. Information on Traditional Chinese Medicine. 2018, 35(6): 101-106. 

[5] Zeng Xingxing. Lu Aijuan. Gao Xiaohui. Ma Ning. Wang Jianfen. The Detection Method of Atractylodes sinensis and its Research Progress [J]. Farm Products Processing, 2019(23):83-85+89. 

[6] Ji Guangquan. Study on immune activity of active ingredients of Atractylodes macrocephala on macrophages and dendritic cells [D]. Guangzhou: South China University of Technology, 2014. 

[7] Wu Tingting, Li Ruliu, Zeng Dan, et al. Research of Atractylodes macrocephala Polysaccharides in Promoting Cell Migration and E-cadherin Expression Through Regulating Calcium Ions [J]. Traditional Chinese Drug Research & Clinical Pharmacology, 2017, 28(2):145-150.  

[8] Xu Pingcui, Shou Dan, Wu Renjie, et al. Study on the Spectrum-effect Relationship between GC-MS Fingerprint and Antioxidant Activity of Volatile Oil from Atractylodis Macrocephalae Rhizoma [J]. Chinese Journal of Modern Applied Pharmacy, 2019, 36(11):1322-1327. 

[9] Huang Yuyan, Ding Xinyu, Sun Wei, et al. Effect of Atractylodes macrocephala Decoction used externally on serum content of TNF-α in mice with auricle infection [J]. Journal of Beijing University of Traditional Chinese Medicine, 2005, 28(6):57-58. 

[10] Zhu Qingjun, Zheng Guangjuan, Zhang Dan. Study on antitumor effect and mechanism of extract of largehead atractylodes rhizome [J]. Journal of Shandong University of Traditional Chinese Medicine, 2006, 30(1):69-71. 

[11] Chen Yunyan. Treatment and nursing of osteohyperplasia of knee joint [J]. Chinese Medicine Modern Distance Education of China, 2013, 11(2):118-119. 

[12] Wang Lei. Study on etiology and symptoms of osteogenesis [J]. China Health and Nutrition Journal, 2013, 000(010):5658-5659. 

[13] Wang Gang, Fan Nina, Zhou Honglun. Clinical treatment of osteopenia [J]. Journal of Liaoning College of Traditional Chinese Medicine, 2005, 7(3):220-220. 

[14] Xu Decong. Objective understanding of bone hyperplasia [J]. Nei Mongol Journal of Traditional Chinese Medicine, 2010, 29(17):70-70. 

[15] He Jianhao. Chen Ming. Discussion on the Relationship between Hyperosteogeny and Zang-fu Organs of Traditional Chinese Medicine [J]. Guangming Journal of Chinese Medicine, 2022, 37(5):777-779. 

[16] Zheng Decai, Li Zhen, Zheng Jie, Guo Chengxiang. Progress in Clinical Research on the Treatment of Scapulohumeral Periarthritis with Chinese Medicine [J]. New Chinese Medicine, 2023, 55(11):46-50. 

[17] Wu Zhiquan, Zhou Guobin, Wu Qiang. Treatment of 125 cases of Lumbar spine bone hyperplasia with acupuncture [J]. Journal of Clinical Acupuncture and Moxibustion, 2001, 17(11):17-18. 

[18] Jin Zhaofeng. Treatment of 217 cases of bone hyperplasia of lumbar spine with Traditional Chinese medicine [J]. Journal of Liaoning University of Traditional Chinese Medicine, 2007, 9(4):119-119. 

[19] Zou Shiguang, Duan Ping, Zhang Qin. Treatment of 510 cases of bone hyperplasia by internal administration and external application of traditional Chinese medicine [J]. Sponsored By Hubei College of Traditional Chinese Medicine, 2003, 25(2):47-47. 

[20] Yu Huiyao. Treating bone hyperplasia from liver and kidney based on the principle of "liver dominates tendons and kidney dominates bone"[J]. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 2014, 20(3):344-345. 

[21] Li Jia, Xie Wanqing, Zheng Hongxin. Connection between Kidney and Articular Carltilage [J]. Chinese Archives of Traditional Chinese Medicine, 2015, 33(6):1344-1346. 

[22] Tan Banghua. Analysis of osteogenesis from renal treatment [J]. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 2008, 14(5):388-389. 

[23] Ma Taomei, Yang Hongyan. Discussion on the pathogenesis and diagnosis and prevention measures of bone hyperplasia [J]. The Medical Forum, 2014, 18(9):1180-1181. 

[24] Ma Xueli,Ma Hongbin,Wei Jinhui et al. Theoretical Basis of Method of Cultivating Soil to Make Water in Treatment of Renal Edema[J].Journal of Practical Traditional Chinese Internal Medicine,2021,35(10):50-52.

[25] Zhai Yahui, Shen Weidong. Treatment of calcaneal bone spurs with single flavor Atractylodes macrocephala [J]. China's Naturopathy, 2020, 28(19):100-101. 

[26] Wang Jun’ao, Chen Wenzhi. Clinical effect of five Elements Shengke therapy on bone hyperplasia [J]. Lishizhen Medicine and Materia Medica Research, 2007, 18(1):180-180. 

[27] Jia Chuan, Yan Yuxing, Xie Zikang. Effect of “Cultivating Soil to Make Water” Method for Treatment of Senile Calcaneal Spur [J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 2018, 24(6):696-700.  

[28] Gong Yingshun, Liu Yongzhong. Clinical observation of 68 cases of bone hyperplasia treated with Atractylodes macrocephala external treatment [J]. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine, 2013, 13(1):88-89.