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Frontiers in Medical Science Research, 2023, 5(12); doi: 10.25236/FMSR.2023.051204.

Prevalence and Risk Factors of Post-COVID-19 Pulmonary Fibrosis: A Meta-analysis


Jing Yang, Huifen Feng, Mingzhu Wang, Shan Zheng, Ning Ai

Corresponding Author:
Huifen Feng

The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China


COVID-19 is a global epidemic caused by severe acute respiratory syndrome coronavirus 2 infection. However, the understanding of long-term respiratory diseases in COVID-19 survivors remains limited.To identify the incidence and risk factors of post-COVID-19 pulmonary fibrosis, a comprehensive search of relevant studies published before the 2nd of April 2023 in PubMed, Embase, Web of Science, and Cochrane Library was conducted, and 18 papers were eligible for this study.  The existing literature evidence showed that about 36.4% of COVID-19 survivors may have developed pulmonary fibrosis, and people with advanced age, male, hypertension, diabetes, glucocorticoid therapy, mechanical ventilation, prolonged hospitalization, and severe COVID-19 are at higher risk of developing this sequela.


COVID-19, SARS-CoV-2, Pulmonary Fibrosis, Risk Factors, Meta-analysis

Cite This Paper

Jing Yang, Huifen Feng, Mingzhu Wang, Shan Zheng, Ning Ai. Prevalence and Risk Factors of Post-COVID-19 Pulmonary Fibrosis: A Meta-analysis. Frontiers in Medical Science Research (2023) Vol. 5, Issue 12: 36-42. https://doi.org/10.25236/FMSR.2023.051204.


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