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Frontiers in Medical Science Research, 2023, 5(12); doi: 10.25236/FMSR.2023.051207.

The Effect of Methyldopa Combined with Rabelol Treatment on Patients with Pregnancy Induced Hypertension

Author(s)

Lingyan Zhang, Xiaoshan Zhang

Corresponding Author:
Xiaoshan Zhang
Affiliation(s)

Shaanxi Provincial People’s Hospital, Xi’an, Shaanxi, 710068, China

Abstract

This paper aims to analyze the therapeutic effect of methyldopa combined with rabelol treatment in patients with pregnancy pregnancy induced hypertension. A total of 70 patients with gestational hypertension diagnosed in our hospital during the period from March 2021 to March 2023 were selected as the research objects. According to different treatment methods, 35 patients treated with magnesium sulfate were included in the reference group, while 35 patients treated with methyldopa combined with rabelol were included in the observation group. Blood pressure and urinary protein levels before and after treatment were compared, hemodynamic indicators,serum indicators and the pregnancy outcomes were compared between the two groups of patients. Result: Before treatment, there was no significant difference in various indicators between the two groups, with no statistical significance (P>0.05). After treatment, the blood pressure, urinary protein level, hemodynamic index, and serum indicators of the observation group were better than those of the reference group, with significant statistical significance (P<0.05). In terms of comparison of adverse pregnancy outcomes, the incidence rates of intrauterine distress, neonatal asphyxia, premature birth, etc. in the observation group were lower than those in the reference group, and the difference was statistically significant (P<0.05). The treatment effect of methyldopa combined with rabelol treatment in patients with gestational hypertension is significant positive, which can control blood pressure and urine protein to reach the ideal range, effectively improve hemodynamic indicators, protect patient vascular endothelial function, and reduce the probability of adverse pregnancy outcomes caused by hypertension. It has great medical significance for ensuring maternal safety and safe production.

Keywords

Methyldopa, Rabelol, Pregnancy induced Hypertension, Hemodynamics, Vascular Endothelium, Adverse Pregnancy, Magnesium Sulfate

Cite This Paper

Lingyan Zhang, Xiaoshan Zhang. The Effect of Methyldopa Combined with Rabelol Treatment on Patients with Pregnancy Induced Hypertension. Frontiers in Medical Science Research (2023) Vol. 5, Issue 12: 57-62. https://doi.org/10.25236/FMSR.2023.051207.

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