Welcome to Francis Academic Press

Frontiers in Medical Science Research, 2024, 6(1); doi: 10.25236/FMSR.2024.060102.

Research Progress of Paraspinal Muscle Fat Infiltration in Osteoporotic Vertebral Compression Fractures

Author(s)

Jie Guo1, Qunli Dou2

Corresponding Author:
Qunli Dou
Affiliation(s)

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China

2Department of Rehabilition, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712000, China

Abstract

The paraspinal muscle fat infiltration and osteoporotic vertebral compression fractures (OVCFs) are common degenerative diseases of the skeletal muscle system in the elderly population, which seriously affect the quality of life. In recent years, many studies have focused on the relationship between paraspinal muscle fat infiltration and common lumbar diseases. However, the impact of this extrinsic factor on the progression of OVCFs has not yet received sufficient attention in clinical practice. This article summarizes the imaging characteristics and clinical relevance of paraspinal muscle fat infiltration in OVCFs, aiming to provide some ideas for the prevention, treatment, and related research of OVCFs and paraspinal muscle fat infiltration.

Keywords

Paraspinal Muscles, Fat Infiltration, Osteoporotic Vertebral Compression Fractures

Cite This Paper

Jie Guo, Qunli Dou. Research Progress of Paraspinal Muscle Fat Infiltration in Osteoporotic Vertebral Compression Fractures. Frontiers in Medical Science Research (2024), Vol. 6, Issue 1: 9-14. https://doi.org/10.25236/FMSR.2024.060102.

References

[1] GUTIERREZ-GONZALEZ R, ROYUELA A, ZAMARRON A. Vertebral compression fractures: pain relief, progression and new fracture rate comparing vertebral augmentation with brace [J]. BMC Musculoskelet Disord, 2023, 24(1): 898.

[2] HWANG S H, CHO P G, KIM K T, et al. What are the risk factors for a second osteoporotic vertebral compression fracture? [J]. Spine J, 2023, 23(11): 1586-1592.

[3] CHO S T, SHIN D E, KIM J W, et al. Prediction of Progressive Collapse in Osteoporotic Vertebral Fractures Using Conventional Statistics and Machine Learning [J]. Spine (Phila Pa 1976), 2023, 48(21): 1535-1543.

[4] HABIBI H, TAKAHASHI S, HOSHINO M, et al. Impact of paravertebral muscle in thoracolumbar and lower lumbar regions on outcomes following osteoporotic vertebral fracture: a multicenter cohort study [J]. Arch Osteoporos, 2021, 16(1): 2.

[5] FORTIN M, LAZÁRY À, VARGA P P, et al. Paraspinal muscle asymmetry and fat infiltration in patients with symptomatic disc herniation [J]. Eur Spine J, 2016, 25(5): 1452-1459.

[6] GUO C, XU S, LIANG Y, et al. Correlation between Degenerative Thoracolumbar Kyphosis and Lumbar Posterior Muscle [J]. J Pers Med, 2023, 13(10).

[7] VITALE J, SCONFIENZA L M, GALBUSERA F. Cross-sectional area and fat infiltration of the lumbar spine muscles in patients with back disorders: a deep learning-based big data analysis [J]. Eur Spine J, 2023.

[8] KADER D F, WARDLAW D, SMITH F W. Correlation between the MRI changes in the lumbar multifidus muscles and leg pain [J]. Clin Radiol, 2000, 55(2): 145-149.

[9] CHEVALIER B, BEDRETDINOVA D, PELLOT-BARAKAT C, et al. Evaluation of the Reproducibility of MR Elastography Measurements of the Lumbar Back Muscles [J]. J Magn Reson Imaging, 2023.

[10] CAPRARIU R, OPREA M, POPA I, et al. Cohort study on the relationship between morphologic parameters of paravertebral muscles, BMI and lumbar lordosis on the severity of lumbar stenosis [J]. Eur J Orthop Surg Traumatol, 2023, 33(6): 2435-2443.

[11] GUO J, XIE D, ZHANG J, et al. Characteristics of the paravertebral muscle in adult degenerative scoliosis with PI-LL match or mismatch and risk factors for PI-LL mismatch [J]. Front Surg, 2023, 10: 1111024.

[12] EKŞI M, ÖZCAN-EKŞI E E. Fatty infiltration of the erector spinae at the upper lumbar spine could be a landmark for low back pain [J]. Pain Pract, 2023.

[13] RONG Z, YANG Z, ZHANG C, et al. Bioinformatics analysis of paravertebral muscles atrophy in adult degenerative scoliosis [J]. J Muscle Res Cell Motil, 2023, 44(4): 287-297.

[14] HAN G, ZHOU S, QIU W, et al. Role of the Paraspinal Muscles in the Sagittal Imbalance Cascade: The Effects of Their Endurance and of Their Morphology on Sagittal Spinopelvic Alignment [J]. J Bone Joint Surg Am, 2023, 105(24): 1954-1961.

[15] LI W, WANG F, CHEN J, et al. MRI‑based vertebral bone quality score is a comprehensive index reflecting the quality of bone and paravertebral muscle [J]. Spine J, 2023.

[16] REITER D A, BELLISSIMO M P, ZHOU L, et al. Increased adiposity is associated with altered skeletal muscle energetics [J]. J Appl Physiol (1985), 2023, 134(5): 1083-1092.

[17] GIORDAN E, DRAGO G, ZANATA R, et al. The Correlation Between Paraspinal Muscular Morphology, Spinopelvic Parameters, and Back Pain: A Comparative Cohort Study [J]. Int J Spine Surg, 2023, 17(5): 627-637.

[18] MUELLNER M, HAFFER H, MOSER M, et al. Changes of the posterior paraspinal and psoas muscle in patients with low back pain: a 3-year longitudinal study [J]. Eur Spine J, 2023, 32(9): 3290-3299.

[19] LARIVIÈRE C, PREUSS R, GAGNON D H, et al. The relationship between clinical examination measures and ultrasound measures of fascia thickness surrounding trunk muscles or lumbar multifidus fatty infiltrations: An exploratory study [J]. J Anat, 2023, 242(4): 666-682.

[20] YOU K H, CHO M, LEE J H. Effect of Muscularity and Fatty Infiltration of Paraspinal Muscles on Outcome of Lumbar Interbody Fusion [J]. J Korean Med Sci, 2023, 38(20): e151.

[21] XIA W, FU H, ZHU Z, et al. Association between back muscle degeneration and spinal-pelvic parameters in patients with degenerative spinal kyphosis [J]. BMC Musculoskelet Disord, 2019, 20(1): 454.

[22] SHAFAQ N, SUZUKI A, MATSUMURA A, et al. Asymmetric degeneration of paravertebral muscles in patients with degenerative lumbar scoliosis [J]. Spine (Phila Pa 1976), 2012, 37(16): 1398-1406.

[23] ZHU D C, LIN J H, XU J J, et al. An assessment of morphological and pathological changes in paravertebral muscle degeneration using imaging and histological analysis: a cross-sectional study [J]. BMC Musculoskelet Disord, 2021, 22(1): 854.

[24] CHEN P, ZHOU Z, SUN L, et al. Quantitative multi-parameter assessment of age- and gender-related variation of back extensor muscles in healthy adults using Dixon MR imaging [J]. Eur Radiol, 2023.

[25] CHENG Y, YANG H, HAI Y, et al. Low paraspinal lean muscle mass is an independent predictor of adjacent vertebral compression fractures after percutaneous kyphoplasty: A propensity score-matched case-control study [J]. Front Surg, 2022, 9: 965332.

[26] LIU Z, ZHANG Y, HUANG D, et al. Quantitative Study of Vertebral Body and Paravertebral Muscle Degeneration Based on Dual-Energy Computed Tomography: Correlation With Bone Mineral Density [J]. J Comput Assist Tomogr, 2023, 47(1): 86-92.

[27] TU Y, TANG G, LI L, et al. A preliminary study on degenerate characteristics of lumbar and abdominal muscles in middle-aged and elderly people with varying bone mass [J]. BMC Musculoskelet Disord, 2023, 24(1): 136.

[28] BECKER L, ZIEGELER K, DIEKHOFF T, et al. Musculature adaption in patients with lumbosacral transitional vertebrae: a matched-pair analysis of 46 patients [J]. Skeletal Radiol, 2021, 50(8): 1697-1704.

[29] EKŞI M, ÖZCAN-EKŞI E E, ORHUN Ö, et al. Proposal for a new scoring system for spinal degeneration: Mo-Fi-Disc [J]. Clin Neurol Neurosurg, 2020, 198: 106120.

[30] MCCLELLAN P E, KESAVAN L, WEN Y, et al. Volumetric MicroCT Intensity Histograms of Fatty Infiltration Correlate with the Mechanical Strength of Rotator Cuff Repairs: An Ex Vivo Rabbit Model [J]. Clin Orthop Relat Res, 2021, 479(2): 406-418.

[31] JEONG H J, KWON J, RHEE S M, et al. New quantified measurement of fatty infiltration of the rotator cuff muscles using magnetic resonance imaging [J]. J Orthop Sci, 2020, 25(6): 986-991.

[32] RUBIN E B, SCHMIDT A M, KOFF M F, et al. Advanced MRI Approaches for Evaluating Common Lower Extremity Injuries in Basketball Players: Current and Emerging Techniques [J]. J Magn Reson Imaging, 2023.

[33] ZHANG T, PENG Y, LI J. Comparison of clinical and radiological outcomes of vertebral body stenting versus percutaneous kyphoplasty for the treatment of osteoporotic vertebral compression fracture: A systematic review and meta-analysis [J]. Jt Dis Relat Surg, 2024, 35(1): 218-230.

[34] CHEN Q, LEI C, ZHAO T, et al. Relationship between sarcopenia/paravertebral muscles and the incidence of vertebral refractures following percutaneous kyphoplasty: a retrospective study [J]. BMC Musculoskelet Disord, 2022, 23(1): 879.

[35] JEON I, KIM S W, YU D. Paraspinal muscle fatty degeneration as a predictor of progressive vertebral collapse in osteoporotic vertebral compression fractures [J]. Spine J, 2022, 22(2): 313-320.

[36] TOKESHI S, EGUCHI Y, SUZUKI M, et al. Relationship between Skeletal Muscle Mass, Bone Mineral Density, and Trabecular Bone Score in Osteoporotic Vertebral Compression Fractures [J]. Asian Spine J, 2021, 15(3): 365-372.

[37] CHEN Z, SHI T, LI W, et al. Role of paraspinal muscle degeneration in the occurrence and recurrence of osteoporotic vertebral fracture: A meta-analysis [J]. Front Endocrinol (Lausanne), 2022, 13: 1073013.

[38] TOKASHIKI T, IGARASHI T, SHIRAISHI M, et al. Evaluation of the association between osteoporotic vertebral compression fractures and psoas major/paraspinal muscle mass and ADC measured on MRI [J]. Skeletal Radiol, 2023.

[39] SI F, YUAN S, ZANG L, et al. Paraspinal Muscle Degeneration: A Potential Risk Factor for New Vertebral Compression Fractures After Percutaneous Kyphoplasty [J]. Clin Interv Aging, 2022, 17: 1237-1248.

[40] LEE D G, BAE J H. Fatty infiltration of the multifidus muscle independently increases osteoporotic vertebral compression fracture risk [J]. BMC Musculoskelet Disord, 2023, 24(1): 508.

[41] KATSU M, OHBA T, EBATA S, et al. Comparative study of the paraspinal muscles after OVF between the insufficient union and sufficient union using MRI [J]. BMC Musculoskelet Disord, 2018, 19(1): 143.

[42] LI Q, SHI L, WANG Y, et al. A Nomogram for Predicting the Residual Back Pain after Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures [J]. Pain Res Manag, 2021, 2021: 3624614.

[43] LI Q, SUN J, CUI X, et al. Analysis of correlation between degeneration of lower lumbar paraspinal muscles and spinopelvic alignment in patients with osteoporotic vertebral compression fracture [J]. J Back Musculoskelet Rehabil, 2017, 30(6): 1209-1214.

[44] WELCH N, MORAN K, ANTONY J, et al. The effects of a free-weight-based resistance training intervention on pain, squat biomechanics and MRI-defined lumbar fat infiltration and functional cross-sectional area in those with chronic low back [J]. BMJ Open Sport Exerc Med, 2015, 1(1): e000050.

[45] ZHAO Y, HUANG M, SERRANO SOSA M, et al. Fatty infiltration of paraspinal muscles is associated with bone mineral density of the lumbar spine [J]. Arch Osteoporos, 2019, 14(1): 99.

[46] ZHOU S, CHEN S, ZHU X, et al. Associations between paraspinal muscles fatty infiltration and lumbar vertebral bone mineral density - An investigation by fast kVp switching dual-energy CT and QCT [J]. Eur J Radiol Open, 2022, 9: 100447.

[47] TURCOTTE A F, KUKULJAN S, DALLA VIA J, et al. Changes in spinal bone density, back muscle size, and visceral adipose tissue and their interaction following a multi-component exercise program in older men: secondary analysis of an 18-month randomized controlled trial [J]. Osteoporos Int, 2020, 31(10): 2025-2035.