In this paper, a meta-analysis was performed to compare the analgesic effect and rapid recovery effect of ultrasound-guided subserratus anterior plane block in upper abdominal surgery. PubMed, Cochrane Library, EMbase, CBM, CNKI, Wanfang and VIP databases were searched by computer from the establishment of the database to May 2024, and a randomized controlled trial on the application of ultrasound-guided subserratus anterior plane block in upper abdominal surgery was included. The following information was extracted from the included literatures: sample size, BMI, sex ratio, age, ASA grade, operation duration, concentration, type and dose of local anesthesia drugs. Meta-analysis was performed using RevMan5.3 software. Results A total of 361 patients were included in 5 studies. The results of meta-analysis showed that compared with the control group, the experimental group can reduce at the resting state pain scores at 6 hours after surgery (MD=-0.63, 95% CI -0.75~ -0.50, P<0.00001) , the resting state pain scores at 12 hours after surgery (MD=-0.61, 95% CI -0.72~ -0.50, P<0.00001), the resting state pain scores at 24 hours after surgery (MD=-0.22, 95% CI -0.30~ -0.14, P<0.00001) , the resting state pain scores at 48 hours after surgery (MD=-0.12, 95% CI -0.20~ -0.04, P=0.005), the amount of sufentanil used during operation (MD=-17.04, 95% CI -18.24~ -15.84, P<0.00001) , the number of postoperative analgesia pump compressions (MD=-12.21, 95% CI -12.54~ -11.88, P<0.00001), the number of postoperative remedial analgesia cases (RR=0.08, 95% CI 0.03~ 0.18, P<0.00001), , the first time to exhaust gas (MD=-16.65, 95% CI -18.95~ -14.35, P<0.00001) , the incidence of nausea and vomiting (RR=0.12, 95% CI 0.06~0.25, P<0.00001) ,and the incidence of dizziness (RR=0.06, 95% CI 0.01~ 0.25, P=0.0001) . There was no significant difference in the first time to get out of bed (MD=-8.99, 95% CI -19.27~ -1.28, P=0.09) , the length of hospitalization (MD=-0.50, 95% CI -1.44~ -0.44, P=0.30) between the two groups. Ultrasound-guided subserratus anterior plane block can effectively improve the analgesic effect and accelerate the rapid recovery of patients through anesthesia in upper abdominal surgery.

Yang Li, Liang Yu, Yuan Libang. Meta-analysis of ultrasound-guided subserratus anterior plane block for analgesia and rapid recovery after upper abdominal surgery. Frontiers in Medical Science Research (2024), Vol. 6, Issue 5: 46-53. https://doi.org/10.25236/FMSR.2024.060507.

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