To analyse the efficacy of early S100B and aEEG in predicting the occurrence of brain injury in preterm infants and neurological outcome at discharge. Eighty-five preterm infants admitted to the neonatology department of our hospital from June 2022 to June 2023 were selected for this study. 80 children were divided into three groups according to the clinical symptoms and imaging findings, i.e., the group with no brain injury, the group with periventricular-intraventricular haemorrhage, and the group with periventricular white matter softening. Comparison of the three groups of patients. Comparing the baseline data of the three groups of patients, the difference was not statistically significant, P>0.05. Comparing the postnatal blood gases and inflammatory indexes of the three groups of patients, it can be seen that the PH and BE of the periventricular-intraventricular haemorrhage group and periventricular white matter softening group were higher than those of the no-injury group, and the periventricular white matter softening group had the highest, P<0.05. The PCT and CRP of the three groups of patients were not statistically significant, and the differences were not statistically significant, P<0.05. In comparison with CRP, the difference was not statistically significant, P>0.05, and the relationship between S100B, aEEG and neurological outcome of preterm infants discharged from the hospital with brain injury has not been clearly established. S100B, aEEG indexes can help to predict early brain injury when preterm infants are discharged from the hospital, which effectively reduces the probability of brain injury in preterm infants, and is worth to be further promoted and applied in the clinic.

Yimeng Sun. The efficacy of early S100B and aEEG in predicting the onset of brain injury in preterm infants and neurological outcome at hospital discharge. Academic Journal of Medicine & Health Sciences (2024), Vol. 5, Issue 9: 56-60. https://doi.org/10.25236/AJMHS.2024.050909.

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