80 patients who were hospitalized in the General Surgery Department of Weifang People's Hospital from March 2022 to October 2023 were selected. The research subjects were divided into three groups: Group A: 40 patients with colorectal adenocarcinoma confirmed by histopathological biopsy; Group B: 40 patients with colon adenomatous polyps confirmed by histopathology; Group C: 40 healthy individuals matched with the first two groups in age and gender as controls. We completed medical history data, laboratory and examination results from all research subjects were collected. The laboratory results included serum cancer markers CA19-9 and CEA, and the gene expression level of miRNA34a. This study explores the potential significance of miRNA34a gene expression as a biomarker for colorectal cancer.

Haiyan Zhu. Expression of serum miRNA34a gene in patients with colorectal cancer. International Journal of Frontiers in Medicine (2024), Vol. 6, Issue 10: 39-43. https://doi.org/10.25236/IJFM.2024.061006.

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