Colonoscopy is the first choice for the diagnosis and treatment of colorectal diseases, and its value and importance are increasing. The quality of bowel preparation before colonoscopy directly affects the accuracy of colonoscopy diagnosis and the safety of colonoscopy treatment. In recent years, more and more attention has been paid to the importance and safety of bowel preparation at home and abroad, and relevant bowel preparation guidelines have been published at home and abroad. This article reviews the research progress of bowel preparation before colonoscopy in recent years, in order to improve the quality of bowel preparation and improve the clinical outcomes of colorectal diseases.

Taoyan Song, Ji Qiu. Research progress on improving the quality of bowel preparation before colonoscopy. International Journal of Frontiers in Medicine (2025), Vol. 7, Issue 1: 13-19. https://doi.org/10.25236/IJFM.2025.070103.

[1] Li, N., Lu, B., Luo, C., Cai, J., Lu, M., Zhang, Y., Chen, H., & Dai, M. (2021). Incidence, mortality, survival, risk factor and screening of colorectal cancer: A comparison among China, Europe, and northern America. Cancer letters, 522, 255–268. 

[2] Chen Xujin, Zhu Xianlan, Ji Lin, Yang Cheng, Zhan Qiang.(2023).Research status of influencing factors of endoscopic insertion time and its relationship with adenoma detection. Chin J Dig Endosc,40(02) : 165-168.

[3] Tongchang Wang, Zixuan He, Fan Xuanming, Li Zhaoshen, Bai Yu.(2024).Current status and progress of research in risk prediction models for colonoscopic bowel preparation failure. Chin J Dig Endosc,41(09) : 741-745.

[4] Lee, Y. J., Kim, E. S., Choi, J. H., Lee, K. I., Park, K. S., Cho, K. B., Jang, B. K., Chung, W. J., & Hwang, J. S. (2015). Impact of reinforced education by telephone and short message service on the quality of bowel preparation: a randomized controlled study. Endoscopy, 47(11), 1018–1027. 

[5] Ergen, W. F., Pasricha, T., Hubbard, F. J., Higginbotham, T., Givens, T., Slaughter, J. C., & Obstein, K. L. (2016). Providing Hospitalized Patients With an Educational Booklet Increases the Quality of Colonoscopy Bowel Preparation. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 14(6), 858–864. 

[6] Jeon, S. C., Kim, J. H., Kim, S. J., Kwon, H. J., Choi, Y. J., Jung, K., Kim, S. E., Moon, W., Park, M. I., & Park, S. J. (2019). Effect of Sending Educational Video Clips via Smartphone Mobile Messenger on Bowel Preparation before Colonoscopy. Clinical endoscopy, 52(1), 53–58.

[7] van der Zander, Q. E. W., Reumkens, A., van de Valk, B., Winkens, B., Masclee, A. A. M., & de Ridder, R. J. J. (2021). Effects of a Personalized Smartphone App on Bowel Preparation Quality: Randomized Controlled Trial. JMIR mHealth and uHealth, 9(8), e26703. 

[8] Chen, G., Zhao, Y., Xie, F., Shi, W., Yang, Y., Yang, A., & Wu, D. (2021). Educating Outpatients for Bowel Preparation Before Colonoscopy Using Conventional Methods vs Virtual Reality Videos Plus Conventional Methods: A Randomized Clinical Trial. JAMA network open, 4(11), e2135576. 

[9] Wen, J., Feng, J., Liu, C., Yang, D., Zhang, Y., Lu, N., Yu, J., Gao, Y., Sheng, R., Wang, J., & Huang, J. (2022). Increased quality of bowel preparation via smartphone WeChat application: a multicenter randomized controlled trial. Videosurgery and other miniinvasive techniques, 17(3), 467–474. 

[10] Shahini, E., Sinagra, E., Vitello, A., Ranaldo, R., Contaldo, A., Facciorusso, A., & Maida, M. (2023). Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature. World journal of gastroenterology, 29(11), 1685–1707. 

[11] Digestive Endoscopy Special Committee of Endoscopic Physicians Branch of Chinese Medical Association (2019).Chinese guideline for bowel preparation for colonoscopy (2019, Shanghai),36(07) : 457-469.

[12] Hassan, C., East, J., Radaelli, F., Spada, C., Benamouzig, R., Bisschops, R., Bretthauer, M., Dekker, E., Dinis-Ribeiro, M., Ferlitsch, M., Fuccio, L., Awadie, H., Gralnek, I., Jover, R., Kaminski, M. F., Pellisé, M., Triantafyllou, K., Vanella, G., Mangas-Sanjuan, C., Frazzoni, L., … Dumonceau, J. M. (2019). Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2019. Endoscopy, 51(8), 775–794. 

[13] Liang Li, Zhong Weilong, Wang Bangmao.(2021).Effect of dietary intervention on blood glucose in colonoscopy patients during intestinal preparation: a meta-analysis. Chin J Dig Endosc,38(04) : 310-314.

[14] Samarasena, J. B., El Hage Chehade, N., Abadir, A., Yu, A., Tran, E., Mai, D., Thieu, D., Albers, G., Parekh, N. K., Karnes, W. E., Chang, K., & Jamal, M. M. (2022). Single-Day Low-Residue Diet Prior to Colonoscopy Demonstrates Improved Bowel Preparation Quality and Patient Tolerance over Clear Liquid Diet: A Randomized, Single-Blinded, Dual-Center Trial. Digestive diseases and sciences, 67(6), 2358–2366. 

[15] Jung, Y. S., Seok, H. S., Park, D. I., Song, C. S., Kim, S. E., Lee, S. H., Eun, C. S., Han, D. S., Kim, Y. S., & Lee, C. K. (2013). A clear liquid diet is not mandatory for polyethylene glycol-based bowel preparation for afternoon colonoscopy in healthy outpatients. Gut and liver, 7(6), 681–687. 

[16] Leszczynski, A. M., MacArthur, K. L., Nelson, K. P., Schueler, S. A., Quatromoni, P. A., & Jacobson, B. C. (2018). The association among diet, dietary fiber, and bowel preparation at colonoscopy. Gastrointestinal endoscopy, 88(4), 685–694. 

[17] Nam, S. J., Kim, Y. J., Keum, B., Lee, J. M., Kim, S. H., Choi, H. S., Kim, E. S., Seo, Y. S., Jeen, Y. T., Lee, H. S., Chun, H. J., Um, S. H., & Kim, C. D. (2018). Impact of diet restriction on bowel preparation for colonoscopy. Medicine, 97(41), e12645. 

[18] Matsumura, T., Arai, M., Ishigami, H., Okimoto, K., Saito, K., Minemura, S., Maruoka, D., Nakagawa, T., Katsuno, T., & Yokosuka, O. (2016). A randomized controlled trial comparing a prepackaged low-residue diet with a restricted diet for colonoscopy preparation: the impact on the results of colonoscopy in adenoma detection. Colorectal disease: the official journal of the Association of Coloproctology of Great Britain and Ireland, 18(1), O37–O42. 

[19] Tamai, N., & Sumiyama, K. (2024). Optimal bowel preparation for colonoscopy. Digestive endoscopy: official journal of the Japan Gastroenterological Endoscopy Society, 10.1111/den.14914. Advance online publication. 

[20] Liu, X., Yu, W., Liu, J., & Liu, Q. (2024). Oral sulfate solution versus polyethylene glycol for bowel preparation before colonoscopy, meta-analysis and trial sequential analysis of randomized clinical trials. Techniques in coloproctology, 28(1), 99. 

[21] Johnson, D. A., Barkun, A. N., Cohen, L. B., Dominitz, J. A., Kaltenbach, T., Martel, M., Robertson, D. J., Richard Boland, C., Giardello, F. M., Lieberman, D. A., Levin, T. R., Rex, D. K., & US Multi-Society Task Force on Colorectal Cancer (2014). Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the US Multi-Society Task Force on Colorectal Cancer. The American journal of gastroenterology, 109(10), 1528–1545. 

[22] Gimeno-García, A. Z., Hernandez, G., Aldea, A., Nicolás-Pérez, D., Jiménez, A., Carrillo, M., Felipe, V., Alarcón-Fernández, O., Hernandez-Guerra, M., Romero, R., Alonso, I., Gonzalez, Y., Adrian, Z., Moreno, M., Ramos, L., & Quintero, E. (2017). Comparison of Two Intensive Bowel Cleansing Regimens in Patients With Previous Poor Bowel Preparation: A Randomized Controlled Study. The American journal of gastroenterology, 112(6), 951–958. 

[23] Parra-Blanco, A., Ruiz, A., Alvarez-Lobos, M., Amorós, A., Gana, J. C., Ibáñez, P., Ono, A., & Fujii, T. (2014). Achieving the best bowel preparation for colonoscopy. World journal of gastroenterology, 20(47), 17709–17726.  

[24] Jiang Miao, TIAN Peiying, Li Huanqing, et al(2014). Comparison of cleaning effect and tolerance of polyethylene glycol electrolyte solution in split doses and single oral bowel preparation program . Gastroenterology, 19(12):712-715.

[25] Wu, L., Cao, Y., Liao, C., Huang, J., & Gao, F. (2011). Systematic review and meta-analysis of randomized controlled trials of Simethicone for gastrointestinal endoscopic visibility. Scandinavian journal of gastroenterology, 46(2), 227–235. 

[26] Albert, J., Göbel, C. M., Lesske, J., Lotterer, E., Nietsch, H., & Fleig, W. E. (2004). Simethicone for small bowel preparation for capsule endoscopy: a systematic, single-blinded, controlled study. Gastrointestinal endoscopy, 59(4), 487–491.