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Academic Journal of Medicine & Health Sciences, 2025, 6(7); doi: 10.25236/AJMHS.2025.060711.

High-Altitude Hypoxia Analysis and Performance Optimization of a Portable Oxygen Concentrator

Author(s)

Xu Xiao

Corresponding Author:
Xu Xiao
Affiliation(s)

Nanjing Yinuoji Medical Technology Co.,Ltd., Nanjing, Jiangsu, China, 210000

Abstract

Extreme high-altitude hypoxia challenges both human physiology and the function of portable oxygen concentrators (POCs). This study evaluates a pulse-based POC at elevations from 4400 m to 7546 m, using real-world data collected during a Mount Muztagh Ata expedition and validated through hypobaric chamber simulations. Results reveal significant performance degradation above 6200 m, with concurrent declines in oxygen concentration and pulse flow, indicating the device's operational limits. To address these issues, three lightweight optimization strategies were developed—compressor rhythm adjustment, battery management refinement, and trigger logic enhancement. Chamber tests at 6000 m and 8000 m demonstrated marked improvements in oxygen output, confirming the effectiveness of these strategies without hardware modification.Additionally, the study assessed the applicability of the U.S. Standard Atmosphere model in high-altitude conditions. While the model generally reflects pressure–oxygen trends, discrepancies at extreme elevations highlight the need for temperature corrections in altitude modeling.These findings offer both field-validated data and engineering solutions to support the design and deployment of portable oxygen systems in high-altitude medical, expeditionary, and emergency scenarios.

Keywords

High-Altitude Hypoxia, Portable Oxygen Concentrator, Field Testing, Performance Optimization, Hypobaric Chamber Experiment

Cite This Paper

Xu Xiao. High-Altitude Hypoxia Analysis and Performance Optimization of a Portable Oxygen Concentrator. Academic Journal of Medicine & Health Sciences (2025), Vol. 6, Issue 7: 86-93. https://doi.org/10.25236/AJMHS.2025.060711.

References

[1] West JB. High-altitude medicine. Am J Respir Crit Care Med. 2012 Dec 15;186(12):1229-37. doi: 10.1164/rccm.201207-1323CI. Epub 2012 Oct 26. PMID: 23103737.

[2] U.S. Standard Atmosphere, 1976. U.S. Government Printing Office, Washington, D.C., 1976.

[3] Bunel V, Shoukri A, Choin F, Roblin S, Smith C, Similowski T, Morélot-Panzini C, Gonzalez J. Bench Evaluation of Four Portable Oxygen Concentrators Under Different Conditions Representing Altitudes of 2438, 4200, and 8000 m. High Alt Med Biol. 2016 Dec;17(4):370-374. doi: 10.1089/ham.2016.0056. PMID: 27959667.

[4] V. Rama Rao, S. Farooq, and W. B. Krantz.Design of a two-step pulsed pressure-swing adsorption-based oxygen concentrator. AIChE Journal, 2009, 55(10): 2622–2632.DOI: 10.1002/aic.11953