The relationship between serum vitamin E (sVE) levels and body mass index (BMI) in the adolescent population has not been thoroughly investigated. This cross-sectional study aimed to explore this association using data from the National Health and Nutrition Examination Survey (NHANES) for adolescents aged 10–19 years. The analysis included 9,428 participants from NHANES cycles conducted between 1999 and 2006. sVE was treated as the primary exposure, while BMI served as the outcome measure. The relationship was evaluated using multivariable linear regression models, controlling for potential confounders such as age, sex, race/ethnicity, and socioeconomic status. Stratified analyses by sex and non-linear curve fitting methods were also performed. Results indicated a significant inverse association between sVE and BMI (β = -2.53, 95% CI: -2.92, -2.14), which was consistent across both males and females (p < 0.0001).Further analysis revealed distinct patterns: a linear trend was observed in females, whereas males exhibited an L-shaped relationship, highlighting potential gender-based variations. These findings suggest that higher sVE levels are associated with lower BMI in US adolescents, with notable differences in the nature of this relationship between sexes.

Jingzhi Jiang, Jiaying Hu, Chen Xia, Jinhao Huang, Yizhuo Chen, Wenyi Zhang, Xuanhua Li, Yingying Wang. Correlation between Vitamin E and Body Mass Index in US Adolescents Aged 10–19 Years: A Cross-Sectional Study. Academic Journal of Medicine & Health Sciences (2025), Vol. 6, Issue 8: 74-82. https://doi.org/10.25236/AJMHS.2025.060810.

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