Biochip technology has transformed medical diagnostics by offering faster, more accurate, and cost-effective solutions for disease detection, personalized medicine, and continuous health monitoring. These compact devices integrate biological molecules onto a small surface to analyze complex biological samples, enabling high-throughput analysis with reduced sample volumes and reagent consumption. Significant advancements in biochip design, such as miniaturization, integration with microfluidics, and the use of novel materials like gold, graphene, and carbon nanotubes, have improved their performance. Despite challenges related to scalability, production costs, data management, and regulatory concerns, biochips are increasingly used in clinical applications for early disease detection, chronic condition monitoring, and point-of-care diagnostics. The future of biochip technology is promising, driven by innovations in organ-on-a-chip and nanotechnology. Collaborative efforts across academia, industry, and healthcare providers are essential to overcoming these challenges and realizing the full potential of biochips in revolutionizing global healthcare systems.

Ruilin Ma. Progress in the Application of Biochip Technology in Medical Examination. Frontiers in Medical Science Research (2025), Vol. 7, Issue 6: 41-49. https://doi.org/10.25236/FMSR.2025.070605.

[1] Sukumaran, C., Indhumathi, K., & Jain, A. (2023). The role of AI in biochips for early disease detection. IEEE Access, 11, 5865-5880. 

[2] Carrara, S., Ghoreishizadeh, S., Olivo, J., & Taurino, I. (2021). Fully integrated biochip platforms for advanced healthcare. Sensors, 12(8), 11013. 

[3] Azizipour, N., Avazpour, R., Rosenzweig, D. H., & Sawan, M. (2020). Evolution of biochip technology: A review from lab-on-a-chip to organ-on-a-chip. Micromachines, 11(6), 599. 

[4] Chaudhary, R. K., Gupta, V., Kalhan, S., Gupta, R., Siddhartha, Neyaz, M. K., & Sharma, J. (2023). The applications of biosensors and biochips for prognosis and diagnosis of diseases. In Biomaterials-Based Sensors: Recent Advances and Applications (pp. 387-411). Singapore: Springer Nature Singapore

[5] Wang, J., Sun, B., & Zhu, Z. (2023). Biochip systems for intelligence and integration. Systems, 11(1), 43.

[6] Newman, J. D., & Turner, A. P. (2007). Historical perspective of biosensor and biochip development. Handbook of Biosensors and Biochips, Wiley-Interscience.

[7] Solovchuk, D. R. (2024). Advances in AI-assisted biochip technology for biomedicine. Biomedicine & Pharmacotherapy, 177, 116997.

[8] Haleem, A., Javaid, M., Singh, R. P., & Suman, R. (2021). Biosensors applications in medical field: A brief review. Sensors International, 2, 100033.