Welcome to Francis Academic Press

Frontiers in Medical Science Research, 2025, 7(6); doi: 10.25236/FMSR.2025.070612.

Study on Targeted Interventions to Reduce the Incidence of Delayed Recovery in Patients Undergoing General Anesthesia

Author(s)

Hongbing Cai, Huakai Liang

Corresponding Author:
Huakai Liang
Affiliation(s)

Department of Anesthesia and Surgery, Maoming People's Hospital, Maoming, 525400, Guangdong, China

Abstract

This study aimed to implement targeted interventions based on baseline data regarding delayed recovery from anesthesia in our institution and to evaluate their effectiveness, as well as to explore their potential for clinical application. An observational study design with a pre-and-post comparison was employed. The period from February to July 2023 served as the baseline for the pre-intervention phase, during which a retrospective analysis of the incidence of delayed recovery in 5,742 patients undergoing general anesthesia was conducted. A systematic literature review was performed to identify key risk factors, which informed the development and implementation of a comprehensive intervention program. This program included enhanced preoperative assessments and optimization, precise administration and antagonism of anesthetic agents, and active intraoperative warming. Data from the same period (February to July) in the subsequent years were used as outcome measures to compare the changes observed in 2024 (n=6,116) and 2025 (n=5,789). Following the implementation of the intervention measures, the incidence of delayed recovery (>2 hours) showed a decreasing trend, from 1.93% in the pre-intervention year (2023) to 1.86% in 2024, and significantly decreased to 1.59% in the second year post-intervention (2025) (P<0.05). This study confirms that targeted interventions based on evidence-based medicine can effectively reduce the incidence of delayed recovery in patients undergoing general anesthesia, thereby optimizing the quality of anesthetic recovery. The proposed intervention program demonstrates scientific validity, effectiveness, and good operability, indicating its potential for broader application in similar healthcare institutions.

Keywords

General anesthesia; Delayed recovery; Quality improvement; Targeted intervention; Application value

Cite This Paper

Hongbing Cai, Huakai Liang. Study on Targeted Interventions to Reduce the Incidence of Delayed Recovery in Patients Undergoing General Anesthesia. Frontiers in Medical Science Research (2025), Vol. 7, Issue 6: 97-101. https://doi.org/10.25236/FMSR.2025.070612.

References

[1] Zhitny V ,Geara E ,Bernstein J , et al.Delayed emergence after general anesthesia: working through the differential diagnosis.[J].Annals of medicine and surgery, 2025,87(7):4563-4566. DOI:10.1097/MS9.0000000000003360.

[2] Zahn P M E ,Lucia D S ,Weinmann C , et al.A core outcome set of measurement instruments for assessing effectiveness and efficacy of perioperative pain management: results of the international IMI-PainCare PROMPT Delphi consensus process.[J].British journal of anaesthesia, 2025,134(5):1460-1473. DOI:10.1016/J.BJA.2025.01.029.

[3] Zhou Xiangli, Yao Jinlan, Wang Xiaoyan. Research Progress on Risk Factors and Predictive Models for Delayed Recovery after General Anesthesia [J]. General Practice Nursing 2025, 23(20):3856-3859.

[4] Mei Weile, Jiang Hongying, Zhu Lina, et al. Research on the Construction of a Delayed Recovery Model for Patients under General Anesthesia Based on Logistic Regression and Random Forest Algorithm [J]. Journal of Qiqihar Medical University, 2020,46(18):1794-1800.

[5] Zhang Min, Zou Qi, Wang Xingjun, et al. Construction and Validation of a Risk Prediction Model for Delayed Recovery from General Anesthesia in Pancreatic Cancer Patients [J]. Modern Clinical Nursing, 2020,24(04):8-14.

[6] Liu Dandan, Sun Jie, Wang Hong. Analysis of Risk Factors for Delayed Recovery during General Anesthesia Recovery Period [J]. Modern Medicine, 2020,53(01):75-79. 

[7] Wang Xingzhi, Xie Chunhua, Zheng Na, et al. Analysis of Influencing Factors and Nursing Strategies for the Recovery Time of Gynecological Surgery Patients under General Anesthesia in the Recovery room [J]. Integrated Traditional Chinese and Western Medicine Nursing (Chinese and English),2022,8(07):139-141.

[8] Fan M ,Zou S ,Wang Y , et al.Systematic Summary of Best Evidence for Preventing Delayed Recovery After General Anesthesia in Older Patients[J].Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses,2025,DOI:10.1016/J.JOPAN.2025.04.001.

[9] Zhang Huan, Wei Ke, Wang Qiaona. Delayed awakening in elderly patients with general anesthesia surgery [J]. The research progress of medical theory and practice, 2023, 4 (8) : 1297-1299. The DOI: 10.19381 / j.i SSN. 1001-7585.2023.08.011.

[10] Youxuan P ,Ying Z ,Xinghua Q .Effects of air-heated blankets on hypothermia and quality of recovery in patients undergoing radical resection for endometrial cancer: A randomized trial[J]. Medicine, 2025,104(27):e42869.DOI:10.1097/MD.0000000000042869.

[11] Wang Xiuli, He Miao, Zhang Weixin, et al. The effect of preoperative pre-warming on improving postoperative hypothermia in patients undergoing thoracoscopic surgery [J]. Nursing Research, 2020,39(21):3699-3703.

[12] Xiong Langyu, Cao Xuehua, Wang Xiaoxia, et al. Meta-analysis of Risk Factors for delayed awakening in patients undergoing General anesthesia surgery [J]. Evidence-based Nursing, 2023, 9(22):4025-4030.

[13] Ying Zhenzhen, Tong Junxia, Tong Qiaoli, et al. The influence of diversified management led by the nursing team on the recovery of elderly patients after general anesthesia [J]. The Chinese general medicine, 2024, 22 (12) : 2172-2176. The DOI: 10.16766 / j.carol carroll nki. Issn 1674-4152.003823.

[14] Wang Yali. Anesthesia recovery room, such as the construction of nursing standard operating process framework and empirical study [D]. Shanxi medical university, 2023. The DOI: 10.27288 /, dc nki. Gsxyu. 2023.000350.

[15] Cao Jin, Xia Jianmei. Participatory hierarchy management application in anesthesia recovery room [J]. Journal of traditional Chinese medicine management journal, 2020, 28 (20) : 208-210. The DOI: 10.16690 / j.carol carroll nki. 1007-9203.2020.20.103.