This study conducted a systematic review of literature on surgical site infection (SSI) prevention and control technologies from PubMed, Web of Science, MEDLINE, EMBASE, EBSCO, Cochrane Library, CNKI, Chinese Medical Journal, Wanfang, VIP, and other databases between May 2015 and May 2025, ultimately including 49 eligible studies. The occurrence of SSI is closely associated with multiple factors including environmental elements (e.g., airborne bacterial counts), instrument contamination, staff hand hygiene, surgical duration, and patients’ underlying conditions. The research highlights evidence-based practices for emerging infection control technologies such as Far-UVC ultraviolet disinfection, plasma technology, thermodynamic sterilization, electric field capture technology, and intelligent surgical environment control systems. It also examines optimized applications of vaporized hydrogen peroxide (VHP) and chemical disinfectants in instrument and surface sterilization, as well as the effectiveness of novel biomaterials like silver-coated nanosheets, biomimetic structures, and responsive antimicrobial coatings in inhibiting bacterial colonization. Additionally, the study explores AI applications in infection prediction and behavioral management, along with the positive impact of management models like PDCA and lean management on reducing SSI incidence. The research also notes discrepancies in international guidelines regarding certain preventive measures, highlighting gaps between evidence-based research and clinical practice. While these emerging technologies demonstrate promising prevention potential, their cost-effectiveness and long-term safety still require further validation. In the future, technology integration and multidisciplinary collaboration should be promoted to develop personalized prevention and control strategies based on risk stratification to achieve more efficient and accurate surgical infection prevention and control.

Yuying Dong, Yiran Xiong, Lulu Gao, Na Ji. Emerging Technologies and Evidence-Based Practice for Infection Prevention and Control in Surgical Sites. Academic Journal of Medicine & Health Sciences (2025), Vol. 6, Issue 9: 100-107. https://doi.org/10.25236/AJMHS.2025.060915.

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