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Academic Journal of Medicine & Health Sciences, 2026, 7(4); doi: 10.25236/AJMHS.2026.070406.

Factors Influencing Fear of Progression in Patients with Diabetic Foot Ulcers: A Qualitative Study

Author(s)

Qiao Yi1, Wen Xiulin2, Tang Kaibo3

Corresponding Author:
Wen Xiulin
Affiliation(s)

¹School of Nursing, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China

²Department of Nursing, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, Shaanxi, China

³College of Life Sciences, Shaanxi Normal University, Xi’an, 710119, Shaanxi, China

Abstract

This study aimed to explore the factors influencing fear of progression (FoP) and the lived experiences of patients with diabetic foot ulcers (DFUs), and to provide evidence to inform home-based foot care, psychological support, and continuing-care interventions. A phenomenological qualitative design, guided by the Common-Sense Model of Self-Regulation (CSM), was used. Fourteen patients with DFUs attending the wound clinic of the First Affiliated Hospital of Xi'an Jiaotong University between March and June 2026 were recruited using purposive and maximum-variation sampling. Semi-structured interviews were conducted. Audio recordings were transcribed within 24 h and analysed using Colaizzi's seven-step method. Three themes and eight subthemes were identified: stressors (fear of amputation and complications, substantial financial burden, and severe restrictions in daily life); illness beliefs (resigned acceptance with passive coping and accepting the illness with active coping); and needs (disease-related knowledge and psychological counselling, guidance for foot self-care, and social support). Fear was closely related to recurrent wounds, pain, functional limitation, financial strain, and negative beliefs about illness controllability. Professional guidance, family support, and compassionate care enhanced confidence in treatment. FoP in patients with DFUs is shaped by disease-related stressors, illness beliefs, and available support resources. In addition to wound management, healthcare professionals should dynamically assess psychological distress and risk of self-harm, provide individualised education, pain management, psychological support, and continuing care, and strengthen family and social support to improve patients' sense of control and self-care capacity.

Keywords

diabetic foot ulcer; fear of progression; Common-Sense Model of Self-Regulation; influencing factors; qualitative research

Cite This Paper

Qiao Yi, Wen Xiulin, Tang Kaibo. Factors Influencing Fear of Progression in Patients with Diabetic Foot Ulcers: A Qualitative Study. Academic Journal of Medicine & Health Sciences (2026), Vol. 7, Issue 4: 44-50. https://doi.org/10.25236/AJMHS.2026.070406.

References

[1] Zhang HF, Xu ZR, Ran XW. Definitions and standards related to diabetic foot. Chin J Diabetes Mellitus. 2020;12(6):363-368.

[2] Armstrong DG, Boulton AJM, Bus SA. Diabetic foot ulcers and their recurrence. N Engl J Med. 2017;376(24):2367-2375.

[3] American Diabetes Association. 11. Microvascular complications and foot care: standards of medical care in diabetes-2020. Diabetes Care. 2020;43(Suppl 1):S135-S151.

[4] Armstrong DG, Tan TW, Boulton AJM, et al. Diabetic foot ulcers: a review. JAMA. 2023;330(1):62-75.

[5] Jing Y, Wang X, Xia L, et al. A cohort study of diabetic patients and diabetic foot ulceration patients in China. Wound Repair Regen. 2015;23(2):222-230.

[6] Dankert A, Duran G, Engst-Hastreiter U, et al. Fear of progression in patients with cancer, diabetes mellitus and chronic arthritis. Rehabilitation (Stuttg). 2003;42(3):155-163.

[7] Dinkel A, Herschbach P. Fear of progression in cancer patients and survivors. Recent Results Cancer Res. 2018;210:13-33.

[8] Beattie AM, Campbell R, Vedhara K. 'Whatever I do it's a lost cause.' The emotional and behavioural experiences of individuals who are ulcer free living with the threat of developing further diabetic foot ulcers: a qualitative interview study. Health Expect. 2014;17(3):429-439.

[9] Wukich DK, Raspovic KM, Suder NC. Patients with diabetic foot disease fear major lower-extremity amputation more than death. Foot Ankle Spec. 2018;11(1):17-21.

[10] Wang YH, Yu QH, Zeng ZH, et al. Predictors of fear of diabetes progression: a multi-center cross-sectional study for patients self-management and healthcare professions education. Front Public Health. 2022;10:910145.

[11] Liu XH, Wang JH, Yang LH, et al. Correlation between dyadic coping and fear of disease progression in patients with hematologic tumors and their spouses. Chin J Nurs. 2025;60(6):717-722.

[12] Leventhal H, Diefenbach M, Elaine A, et al. Illness cognition: using common sense to understand treatment adherence and affect cognition interactions. Cognit Ther Res. 1992;16(2):143-163.

[13] van Netten JJ, Bus SA, Apelqvist J, et al. Definitions and criteria for diabetic foot disease. Diabetes Metab Res Rev. 2020;36(S1):e3268.

[14] Liu M. Application of Colaizzi's seven-step method in phenomenological research data analysis. J Nurs Sci. 2019;34(11):90-92.

[15] Abu-Qamar MZ. Knowledge and practice of foot self-care among Jordanians with diabetes: an interview-based survey study. J Wound Care. 2014;23(5):247-254.

[16] Crawford F, Cezard G, Chappell FM, et al. The development and validation of a multivariable prognostic model to predict foot ulceration in diabetes using a systematic review and individual patient data meta-analyses. Diabet Med. 2018;35(11):1480-1493.

[17] Toygar I, Hançerlioğlu S, Uuku T, et al. Effect of an educational intervention based on Bandura's theory on foot care self-efficacy in diabetes: a prospective quasi-experimental study. Int J Low Extrem Wounds. 2022;21(4):414-419.

[18] Coffey L, Mahon C, Gallagher P. Perceptions and experiences of diabetic foot ulceration and foot care in people with diabetes: a qualitative meta-synthesis. Int Wound J. 2019;16(1):183-210.

[19] Li W, Wu ZH, Li YY, et al. Association between anxiety and depression in patients with diabetic foot. J Mudanjiang Med Univ. 2020;41(1):50-52.

[20] Writing Group of the Expert Consensus on Multidisciplinary Prevention and Treatment of Diabetic Foot. Expert consensus on multidisciplinary prevention and treatment of diabetic foot (2020 edition). Chin J Burns. 2020;36(8):E01-E52.

[21] Wu JY, Ning L, Tang AM. Research progress on the clinical application of patient-reported outcomes in patients with diabetes. Nurs J Chin PLA. 2020;37(8):57-60.

[22] Jin XC, Wu R, Sun QZ, et al. Integrative study of clinical nursing practice guidelines for health education in patients with high-risk diabetic foot. J Nurs. 2020;27(10):49-53.

[23] Crocker RM, Tan TW, Palmer KNB, et al. The patient's perspective of diabetic foot ulceration: a phenomenological exploration of causes, detection and care seeking. J Adv Nurs. 2022;78(8):2482-2494.

[24] Hill A, Ellis M, Gillison F. Qualitative exploration of patient and healthcare professional perspectives on barriers and facilitators to foot self-care behaviors in diabetes. BMJ Open Diabetes Res Care. 2022;10(6):e003034.

[25] Kragh Nielsen M, Bergenholtz H, Madsen UR. Thoughts and experiences on leg amputation among patients with diabetic foot ulcers. Int J Qual Stud Health Well-being. 2022;17(1):2009202.

[26] Tan TW, Crocker RM, Palmer KNB, et al. A qualitative study of barriers to care-seeking for diabetic foot ulceration across multiple levels of the healthcare system. J Foot Ankle Res. 2022;15(1):56.

[27] Manalu NV, Yunitasari E, Kotijah S, et al. How diabetic foot ulcer patients can self-treat wound care: an integrative literature review. SAGE Open Nurs. 2024;10:23779608241274219.

[28] Hansen CA, Hjelmgaard CMH, Kristensen MØ, et al. Patient involvement in diabetes-related foot ulcers: what do patients need and prefer when undergoing treatment at multidisciplinary outpatient foot centres? A phenomenological hermeneutic study. Int Wound J. 2024;21(12):e70128.