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Frontiers in Medical Science Research, 2022, 4(10); doi: 10.25236/FMSR.2022.041010.

Progress in diagnostic staging of myelodysplastic syndrome

Author(s)

Qizhuo Hou1, Kongzhen Gu1,2

Corresponding Author:
Kongzhen Gu
Affiliation(s)

1Xiangya School of Medicine, Central South University, Changsha, 410031, Hunan, China

2Department of Laboratory Medicine, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China

Abstract

Myelodysplastic syndromes (MDS) are a group of acquired heterogeneous clonal disorders that originate from hematopoietic stem cells. It is characterized by a reduction in one or more blood lines in the myeloid system with abnormal development, pathological hematopoiesis and a high risk of transformation to acute myeloid leukemia (AML). In 2016, the World Health Organization (WHO) revised the diagnostic staging criteria for MDS, but with the development of next-generation sequencing (NGS) technology, the diagnostic staging of MDS has opened a new era of accurate diagnosis and individualized treatment. In this paper, we review the diagnostic typing of MDS.

Keywords

Myelodysplastic syndrome; diagnostic typing; next-generation sequencing technology; precise diagnosis

Cite This Paper

Qizhuo Hou, Kongzhen Gu. Progress in diagnostic staging of myelodysplastic syndrome. Frontiers in Medical Science Research (2022) Vol. 4, Issue 10: 56-61. https://doi.org/10.25236/FMSR.2022.041010.

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