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Academic Journal of Medicine & Health Sciences, 2023, 4(4); doi: 10.25236/AJMHS.2023.040405.

Diagnosis, Treatment, and Prevention of Acute-on-Chronic Liver Failure with Bacterial Infections


Liangwu Chen1, Weimin Zhu2

Corresponding Author:
Weimin Zhu

1Department of Infectious Disease, The Frist Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, 400016, China

2Department of Infectious Disease, The Frist Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, 400016, China


Acute-on-chronic liver failure (ACLF) is a syndrome that can lead to severe dysfunction and decompensation of liver synthesis, metabolism, detoxification, and biotransformation. ACLF with bacterial infections can lead to making the disease worse and increasing short-term mortality. However, the clinical manifestations of patients are not typical and the waiting time for bacterial culture is long. Finding reliable early diagnostic indicators, starting effective treatment, and giving timely preventive measures can reduce the mortality of patients and improve the clinical prognosis. This article describes the mechanism of acute-on-chronic liver failure with bacterial infections, summarizes its early diagnostic indicators, and reviews the treatment and prevention methods.


acute-on-chronic liver failure, bacterial infections, diagnosis, therapy, prevention

Cite This Paper

Liangwu Chen, Weimin Zhu. Diagnosis, Treatment, and Prevention of Acute-on-Chronic Liver Failure with Bacterial Infections. Academic Journal of Medicine & Health Sciences (2023) Vol. 4, Issue 4: 26-32. https://doi.org/10.25236/AJMHS.2023.040405.


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