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International Journal of Frontiers in Medicine, 2023, 5(4); doi: 10.25236/IJFM.2023.050403.

Application of robotic surgery in cytoreductive surgery for advanced ovarian cancer


Wang Rong, Chen Wanli, Wu Jialin, Wu Yingyu, Xiao Lin

Corresponding Author:
Xiao Lin

Department of Gynecology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China


It has been a hot topic to correctly evaluate the effect of operation mode and operation approach on patient survival. The robotic surgery system has many advantages such as flexible, stable and delicate, which has excellent results in complex surgeries compared with laparoscopic surgery. The robotic surgery has been applied in the stage operation of early ovarian cancer, the debulking surgery of advanced ovarian cancer and the debulking surgery of recurrent ovarian cancer. This review summarizes the application and controversy of minimally invasive surgery in the treatment of advanced ovarian cancer, and focuses on the feasibility and safety of robotic systems.


Robotic surgery; Cytoreductive surgery; Laparoscopy; Ovarian cancer

Cite This Paper

Wang Rong, Chen Wanli, Wu Jialin, Wu Yingyu, Xiao Lin. Application of robotic surgery in cytoreductive surgery for advanced ovarian cancer. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 4: 10-15. https://doi.org/10.25236/IJFM.2023.050403.


[1] PETRILLO M, VIZZIELLI G, FANFANI F, et al. Definition of a dynamic laparoscopic model for the prediction of incomplete cytoreduction in advanced epithelial ovarian cancer: proof of a concept [J]. Gynecol Oncol, 2015, 139(1):5-9.

[2] RUTTEN M J, VAN MEURS H S, VAN DE VRIE R, et al. Laparoscopy to Predict the Result of Primary Cytoreductive Surgery in Patients With Advanced Ovarian Cancer: A Randomized Controlled Trial [J]. J Clin Oncol, 2017, 35(6):613-621.

[3] FAGOTTI A, VIZZIELLI G, COSTANTINI B, et al. Learning curve and pitfalls of a laparoscopic score to describe peritoneal carcinosis in advanced ovarian cancer [J]. Acta Obstet Gynecol Scand, 2011, 90(10):1126-1131.

[4] MELAMED A, NITECKI R, BORUTA D M, 2ND, et al. Laparoscopy Compared With Laparotomy for Debulking Ovarian Cancer After Neoadjuvant Chemotherapy [J]. Obstet Gynecol, 2017, 129(5): 861-869.

[5] PEREIRA A, MAGRINA J F, MAGTIBAY P M, et al. Does MIS Play a Role in the Treatment of Advanced Ovarian Cancer? [J]. Cancers (Basel), 2022, 14(15).

[6] NITECKI R, RAUH-HAIN J A, MELAMED A, et al. Laparoscopic cytoreduction After Neoadjuvant ChEmotherapy (LANCE) [J]. Int J Gynecol Cancer, 2020, 30(9):1450-1454.

[7] POMEL C, AKLADIOS C, LAMBAUDIE E, et al. Laparoscopic management of advanced epithelial ovarian cancer after neoadjuvant chemotherapy: a phase II prospective multicenter non-randomized trial (the CILOVE study) [J]. Int J Gynecol Cancer, 2021, 31(12):1572-1578.

[8] JOCHUM F, VERMEL M, FALLER E, et al. Three and Five-Year Mortality in Ovarian Cancer after Minimally Invasive Compared to Open Surgery: A Systematic Review and Meta-Analysis [J]. J Clin Med, 2020, 9(8).

[9] ZENG S, YU Y, CUI Y, et al. Efficacy and Safety of Minimally Invasive Surgery Versus Open Laparotomy for Interval Debulking Surgery of Advanced Ovarian Cancer After Neoadjuvant Chemotherapy: A Systematic Review and A Meta-Analysis [J]. Front Oncol, 2022, 12:900256.

[10] CECCARONI M, ROVIGLIONE G, BRUNI F, et al. Laparoscopy for primary cytoreduction with multivisceral resections in advanced ovarian cancer: prospective validation. "The times they are a-changin"? [J]. Surg Endosc, 2018, 32(4):2026-2037.

[11] Hou Z, Niu Z R, Guo H Y, et al. Comparison of laparoscopic and open primary tumor cytoreductive surgery for advanced epithelial ovarian cancer [J]. Chinese Journal of Minimally Invasive Surgery, 2021, 21(03):199-204

[12] FARGHALY S A. Robotic-assisted laparoscopic anterior pelvic exenteration in patients with advanced ovarian cancer: Farghaly's technique [J]. Eur J Gynaecol Oncol, 2010, 31(4):361-363.

[13] FEUER G A, LAKHI N, BARKER J, et al. Perioperative and clinical outcomes in the management of epithelial ovarian cancer using a robotic or abdominal approach [J]. Gynecol Oncol, 2013, 131(3): 520-524.

[14] MAGRINA J F, ZANAGNOLO V, NOBLE B N, et al. Robotic approach for ovarian cancer: perioperative and survival results and comparison with laparoscopy and laparotomy [J]. Gynecol Oncol, 2011, 121(1):100-105.

[15] ZHANG Y, GRANT M S, ZHANG X, et al. Comparing Laparotomy with Robot-assisted Interval Debulking Surgery for Patients with Advanced Epithelial Ovarian Cancer Receiving Neoadjuvant Chemotherapy [J]. J Minim Invasive Gynecol, 2021, 28(6):1237-1243.

[16] ABITBOL J, GOTLIEB W, ZENG Z, et al. Incorporating robotic surgery into the management of ovarian cancer after neoadjuvant chemotherapy [J]. Int J Gynecol Cancer, 2019, 29(9):1341-1347.

[17] PSOMIADOU V, PRODROMIDOU A, FOTIOU A, et al. Robotic interval debulking surgery for advanced epithelial ovarian cancer: current challenge or future direction? A systematic review [J]. J Robot Surg, 2021, 15(2):155-163.