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International Journal of Frontiers in Medicine, 2023, 5(4); doi: 10.25236/IJFM.2023.050414.

Research progress on effects of 3D-printed antler powder scaffolds on biological behavior of macrophages


Zhang Xinyi1, Duan Yuyi1, Geng Runa1, Aypere Abutejalel1, Nafisha Yalikun1, Han Xiangzhen2

Corresponding Author:
Han Xiangzhen

1School of Stomatology, Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China

2Stomatology Hospital, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China


Macrophages are important cells in the regulation of host immune and inflammatory response. Host inflammatory response is the normal response of tissue to injury and foreign body. The intensity and persistence of inflammation affect the biocompatibility and stability of biomaterials in vivo. Therefore, its responsiveness to biomaterials plays an important role in the cognitive material-host response. The effect of scaffold material on the biological behavior of macrophages plays an important role in the process of bone tissue regeneration. Calcined deer horn cancellous bone is a new type of bone graft material. By studying the influence of deer horn powder /PVA scaffold material on the biological behavior of macrophages, the relationship between subtypes of macrophages and bone regeneration is understood, and the advantages of deer horn powder as a new bone graft material are understood.


red deer horn powder, macrophage, polarization, bone tissue regeneration

Cite This Paper

Zhang Xinyi, Duan Yuyi, Geng Runa, Aypere Abutejalel, Nafisha Yalikun, Han Xiangzhen. Research progress on effects of 3D-printed antler powder scaffolds on biological behavior of macrophages. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 4: 86-90. https://doi.org/10.25236/IJFM.2023.050414.


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