Primary nephrotic syndrome in children is a group of clinical syndromes caused by the significant increase in the permeability of glomerular filtration membrane to plasma albumin and the loss of a large amount of albumin from urine due to various reasons. It is sensitive to hormones but easy to relapse, and may be dependent on hormones or resistant to drugs after repeated attacks, thus affecting the prognosis. Clinically, it is summarized as refractory nephrotic syndrome in children. Respiratory tract infection is one of the main factors causing the recurrence of refractory nephrotic syndrome in children. Yupingfeng Powder is the prescription of fuzheng Gubenjing, simple and effective, and it is widely used in clinic. Modern research confirmed that Yupingfeng can promote immunoglobulin IgA, IgG, IgE and monocyte macrophages, improve the immune function of the body, in recent years YuPingFeng alone or combined western medicine treatment of children repeated respiratory tract infection shows a unique curative effect and advantages, thus reducing the recurrence frequency of pediatric refractory nephrotic syndrome and frequency.

Miao Peng, Chunying Liu, Caili Cao, Yuxin Jian. Effect and mechanism of Yupingfeng Powder on preventing recurrent respiratory tract infection in children with refractory nephrotic syndrome. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 5: 28-32. https://doi.org/10.25236/IJFM.2023.050505.

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