Welcome to Francis Academic Press

International Journal of Frontiers in Medicine, 2023, 5(5); doi: 10.25236/IJFM.2023.050506.

Research progress of traditional Chinese and western medicine on myocardial dysfunction in sepsis

Author(s)

Zhang Lin1, Ma Jing2

Corresponding Author:
Ma Jing
Affiliation(s)

1Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China

2Department of Traditional Chinese Medicine, Xijing Hospital, the Fourth Military Medical University, Xi'an, 710032, Shaanxi, China

Abstract

Sepsis is a dangerous disease with high mortality, which brings a huge economic burden to patients and society and has attracted more and more attention from the society. Sepsis is a systemic infectious disease. The dysregulated host immune response caused by infection is easy to cause multiple organ damage, and the heart is one of the most vulnerable organs, which leads to septic myocardial dysfunction. Therefore, the treatment of sepsis-induced myocardial dysfunction is a difficult and important point. In recent years, traditional Chinese medicine has shown great advantages in the treatment of this disease. Through the combination of disease differentiation and syndrome differentiation, the overall treatment rate can be significantly improved. Therefore, it is a bright prospect for the treatment of sepsis myocardial dysfunction with integrated traditional Chinese and western medicine. In recent years, the combination of traditional Chinese medicine and western medicine has made some progress in the treatment of sepsis, which has significantly reduced the mortality of sepsis.

Keywords

Integrated traditional Chinese and Western medicine; Sepsis; Myocardial dysfunction; Research progress

Cite This Paper

Zhang Lin, Ma Jing. Research progress of traditional Chinese and western medicine on myocardial dysfunction in sepsis. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 5: 33-38. https://doi.org/10.25236/IJFM.2023.050506.

References

[1] Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for Sepsis and septic shock (Sepsis-3) [J]. Jama, 2016, 315 (8): 801-810. 

[2] Jiang Wei, Du Bin. Epidemiological status of sepsis in China [J]. J Med Postgraduate, 2019, 32(01):5-8. 

[3] Yue L, Deng X, Yang M, et al. Elevated B-type natriuretic peptide (BNP) and soluble thrombomodulin (sTM) indicates severity and poor prognosis of sepsis [J]. Annals of Palliative Medicine, 2021. 

[4] L 'Heureux M, Sternberg M, Brath L, et al. Sepsis-induced cardiomyopathy: L 'Heureux M, Sternberg M, Brath L, et al. Sepsis-induced cardiomyopathy: a comprehensive review [J]. Current Cardiology Reports, 2020, 22(5): 1-12. 

[5] Huang Danhong, Jiang Xiaodong. [J]. North Pharmacy, 2014, 11(08):102-103. 

[6] Cao Shuhua, Wang Jinda, Li Yinping. From "Simultaneous treatment of bacteria and toxin" to "four syndromes and four methods": the deepening and improvement of syndrome differentiation thinking in the treatment of multiple organ dysfunction syndrome with integrated traditional Chinese and Western medicine [J]. Chinese Journal of Critical Care and Emergency Medicine, 2005(11):7-9. 

[7] Rhodes A, Evans L E, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016 [J]. Intensive care medicine, 2017, 43: 304-377. 

[8] Zhou Haijun, Zheng Wuhong, Zhuo Xiuming, Ke Jun. Comparison of levosimendan and dobutamine in the treatment of septic cardiomyopathy [J]. Journal of Trauma and Emergency Medicine, 2021, 9(02):80-84. 

[9] Hiromi T, Toida C, Muguruma T, et al. Two cases with intra‐aortic balloon pumping use for severe septic cardiomyopathy [J]. Acute Medicine & Surgery, 2009, 33 (2): 68-76. 2017, 4(4): 446-450. 

[10] Min Long, Yuqin Zhang, Yu Yue, Yumei Zhang, Yunhua Yang, Jian Liu, Qinge Meng, Fang Wang, Zhonglan Qi. Effect of Huanglian-Jiedu decoction combined with Western medicine on myocardial injury in patients with sepsis [J]. Shaanxi Traditional Chinese Medicine, 2021, 43(03):329-333. 

[11] Han Ning, Cui Xiaozheng. Effects of Xuebijing injection on myocardial injury markers and inflammatory markers in patients with sepsis complicated with myocardial injury [J]. Chinese Hospital Medication Evaluation and Analysis, 2012, 22(06):719-721+725. 

[12] Bejjani F, Evanno E, Zibara K, et al. The AP-1 transcriptional complex: Local switch or remote command [J]. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 2019, 1872(1): 11-23. 

[13] Hu Man, Liu Fusheng, Huang Po, Wang Sumei, Fang Xiaolei. Efficacy and Safety of Shenfu Injection for Sepsis-related Myocardial Injury:A Systematic Review and Meta-analysis [J]. Journal of Emergency in Traditional Chinese Medicine, 2022, 31(7):1129-1133. 

[14] Li Zhengliang. The protective effect of metoprolol combined with Astragalus injection on myocardial injury in patients with septic shock [J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2018, 27(34): 3839-3842. 

[15] Sun Fangyuan, Zhang Wei, Yuan Lin, Wang Miao, Xu Kailiang, Han Yaoguo, Chen Gang, Shen Weihong. Effects of electroacupuncture on the expression of microRNA-133a in patients with septic myocardial injury [J]. Journal of Bengbu Medical College, 2020, 45(03):335-337+341.