Objective To investigate the clinicopathological features of ossifyingfasciitis. Methods The clinical, imaging and pathological data of a case of ossifying fasciitis diagnosed in Aikang Pathology Department of Huangshi in June 2023 were collected, and the relevant literature was reviewed. Results A 36-year-old male patient with ossifying fasciitis was located in the elbow of the right upper limb. The lesion was relatively clear and consisted of chaotic proliferation of fibroblasts/myofibroblasts and osteoid tissues with varying degrees of maturity. The fusiform fibroblasts are mild in form and occasionally have mitotic signs, which are morphologically similar to myositis ossificans. Osteoid tissues were of varying maturity and irregular shape. Osteoblasts could be seen around them and were randomly distributed in fibrous tissues in the form of cords. Immunohistochemistry; Vimentin spindle cells (+), SMA (+) and caldesmon (-), desmin (-) and B - catenin (-), S - 100 (-) and CD34 (-). CK (-). Conclusion Fasciitis ossificans is a rare benign lesion, its clinicopathological features are very similar to myositis ossificans, and the prognosis is good after complete resection. No metastasis or malignant transformation has been reported.

Zhou Zhiling. Pathological Observation and Literature Clinical Review of Ossifyingfasciitis. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 7: 52-56. https://doi.org/10.25236/IJFM.2023.050708.

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