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International Journal of Frontiers in Medicine, 2023, 5(7); doi: 10.25236/IJFM.2023.050714.

Therapeutic Effect of Guilu Congnao Granules Combined with Acupuncture on Syndrome of Deficiency of Liver and Kidney with Mental Retardation


Shengli Du1, Yutang Liu2

Corresponding Author:
Yutang Liu

1Shaanxi University of Traditional Chinese Medicine, Xianyang, 712064, China

2Xi'an Hospital of Traditional Chinese Medicine Encephalopathy, Xi'an, 710032, Shaanxi, China


To observe the clinical effect of Guilu Congnao granules combined with acupuncture in the treatment of mental retardation syndrome of liver and kidney insufficiency. Sixty children with mental retarding syndrome of liver and kidney deficiency were randomly divided into two groups. The treatment group was given Guilucongnao granules combined with acupuncture and rehabilitation training, while the control group was given rehabilitation training only. The children in both groups were treated for three months, and the intelligence level of the children in both groups was statistically measured by Nimodipine before and after treatment. The Chinese revised Wechsler Childhood Intelligence Scale was used to compare the efficacy before and after treatment. The overall efficacy of the treatment group was better than that of the control group, and the comparison between groups was statistically significant (p< 0.05). The curative effect of Gulumcongnao granules combined with acupuncture on children with mental retardation syndrome of liver and kidney insufficiency is obvious.


Gulumcongnao Granules, Acupuncture, Mental Retardation, Yndrome of Liver and Kidney Insufficiency, Rehabilitation Training

Cite This Paper

Shengli Du, Yutang Liu. Therapeutic Effect of Guilu Congnao Granules Combined with Acupuncture on Syndrome of Deficiency of Liver and Kidney with Mental Retardation. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 7: 87-92. https://doi.org/10.25236/IJFM.2023.050714.


[1] Wang Feng, Gao Jing, Zhang Xuejiao, et al. The Effect of Enlightening training on the Development of Neuropsychological function in 3~6 years old children with mental retardation. Frontiers of Medicine, 2018, 8(35):385-386. 

[2] Hu Yamei, Jiang Zafang, Zhufutang Practical Pediatrics. 7th Ed. Beijing: People's Medical Publishing House, 2005:1894-1895. (in Chinese) 

[3] Li Lin, Li Xiaojie. Progress in etiology of cerebral palsy in children. Chinese Journal of Rehabilitation Medicine, 2004. 19 (12): 941-944. 

[4] Bryan Kolb, Ian Q. Whishaw. Plasticity of the Brain and Behavior. Annual Review of Psychology, 1998, 49(1). 

[5] Hubel Dh and Wiesel Tn. The period of susceptibility to the physiological effects of unilateral eye closure in kittens. Journal of Physiology. 1970, 206:419-436. 

[6] Thamas E, et al. Neural plasticity and development. Nelsonca, Lucianm. Handbook of Development Cognitive Neuroscience. Massachusertts Institute of Technology, 2001:191-201. 

[7] Deng Hongzhu, Zou Xiaobing. Clinical analysis of intellectual disability. Chinese Journal of Practical Pediatrics, 2014, 07:485-489. 

[8] Kong Mian, Liu Zhenhuan, Huang Chen. Guidelines for Clinical diagnosis and treatment in pediatrics of Traditional Chinese Medicine: Mental retardation. Journal of Pediatrics of Traditional Chinese Medicine, 2016, 12(2):1-5. 

[9] Jiang Yonghui, Zhou Wenhao, Luo Feihong. Research Progress and implications of Mental retardation. Chinese Journal of Evidence-based Pediatrics, 2012, 7 (4):241-244. 

[10] Zhang Xiuling, Li Jiping, Qin Mingjing, et al. Development of Gesell Developmental Diagnostic Scale for 3. 5 to 6 years of age: Beijing Revision. Chinese Journal of Clinical Psychology, 1994, 2(3):148-150, 191-192. 

[11] Li Jiandao, Zhang Huanjun, Wang Shuhao, et al. Therapeutic effect of Jin Sanjin combined with rehabilitation training on mental retardation. Shanghai Journal of Acupuncture, 2017, 36 (1):27-29. 

[12] Li Huawei, Ma Bingxiang, Feng Yu. Clinical observation of scalp acupuncture in treatment of speech disorder in children with cerebral palsy. Modern distance Education of Chinese Traditional Medicine, 2010, 8 (24):37-38.