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International Journal of Frontiers in Medicine, 2023, 5(7); doi: 10.25236/IJFM.2023.050716.

Advances in the Role of Active Ingredients of Astragalus in Lung Cancer-Related Signaling Pathways


Ruifang Cui1, Renting Li2

Corresponding Author:
Renting Li

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China


Modern clinical studies have shown that the Chinese herbal medicine Astragalus plays an important role in reducing the toxic side effects of radiotherapy and chemotherapy for lung cancer, improving the quality of survival, stabilizing the tumor, and preventing tumor recurrence and metastasis after surgery. Due to the complex pathogenesis of lung cancer, the wide range of effective components of Astragalus and the complex action pathways, this paper reviews the pharmacological mechanisms of Astragalus in lung cancer treatment and the related signaling pathways by integrating the literature on the anti-lung cancer of Astragalus at home and abroad and combining the main components of Astragalus, methyloside, polysaccharides and flavonoids, in order to provide an effective pharmacological basis for the treatment of lung cancer by Astragalus and to facilitate the further development and utilization of Astragalus resources.


astragalus active ingredients; lung cancer; signaling pathway

Cite This Paper

Ruifang Cui, Renting Li. Advances in the Role of Active Ingredients of Astragalus in Lung Cancer-Related Signaling Pathways. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 7: 101-107. https://doi.org/10.25236/IJFM.2023.050716.


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