Over the past few decades, cancer research has advanced substantially reaveling illumination on previously enigmatic aspects of cancer biology and paving the way for revolutionary therapeutic approachces. However, the resources and methods of treating cancers are still less in number which people still felt threatened by it passively. There is a nanosized  extracellular vesicle (EV) called exosome have been widely used for treating cancer as well as research of it in nowadays, which contains and transports proteins, lipids, and nucleic acids. We discuss how exosome is preserved currently which uses different methods and techiniques. Next, we compared what kind of technology could be the most efficient in purifying exosome. We also point out that exosomes can either suppress or promote the cancer cells, depending on what they carrying and what kinds of enviorment they in. In this comprehensive review, we will focus on the mechanism of cargo sorting and how exosome is created and characterised from endosomes, which contains how they distribute specific cargo and how exosome carries those. Eventually, we provide a brief view of clinical courses and application of exosomes in canaer therapy in recent years and prospects for exosomes being used in further medical research.

Jaewon Choi, Peiqi Lin. Advances in exosomes for cancer therapy. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 8: 55-59. https://doi.org/10.25236/IJFM.2023.050807.

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