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International Journal of Frontiers in Medicine, 2023, 5(8); doi: 10.25236/IJFM.2023.050816.

Oral health and oral health management in children with acute lymphoblastic leukemia


Lan Lan1, Yuwei Han1, Yishan Liu1,2

Corresponding Author:
Yishan Liu

1Department of Pediatric Prevention of Stomatology, The First Affiliated Hospital (Affiliated Stomatological Hospital) of Xinjiang Medical University, Urumqi, 830054, China

2Xinjiang Uygur Autonomous Region Institute of Stomatology, Urumqi, Xinjiang Uygur Autonomous Region, 830054, China


Acute lymphoblastic leukemia is the most common type of childhood leukemia, and most children with acute lymphoblastic leukemia show impaired oral health, high risk of dental caries, altered caries related factors and oral flora disorders, with significantly higher periodontitis status and oral mucous inflammation. Dental morphological disorders are more common in children with ALL than in healthy children. In children with ALL, malocclusion due to small dental clusters may also trigger TMJ disorders. In recent years, the treatment and prognosis of children with acute lymphoblastic leukemia have been significantly improved, but the disease and its therapeutic measures can lead to a variety of oral complications, which affects further treatment and is not conducive to disease control. Maintaining oral health, improving related symptoms of patients and reducing the occurrence of complications has received much attention. In order to improve the quality of life of children, this paper reviews the oral health status and oral health management of children with acute lymphoblastic leukemia, providing clinical reference.


Acute lymphoblastic leukemia; Childhood leukemia; Chemotherapy; Complications; Oral care; Oral disease; Oral infection; Oral health management

Cite This Paper

Lan Lan, Yuwei Han, Yishan Liu. Oral health and oral health management in children with acute lymphoblastic leukemia. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 8: 115-120. https://doi.org/10.25236/IJFM.2023.050816.


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