Wenxian An1, Yaying Xie2, Yuting Zhang1
1Inner Mongolia Medical University, Hohhot, China
2Department of Anesthesiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China
As a transition metal with REDOX properties, copper plays an indispensable role as an enzyme cofactor in a variety of biochemical processes. It is absorbed by small intestinal epithelial cells, transported in blood, stored in liver, and excreted in bile to maintain systemic copper homeostasis. However, when the excretion and absorption of copper in the body are unbalanced, such as the proportion of excretion, the copper concentration will exceed the upper limit of the cellular copper concentration threshold, which will lead to cell metabolism disorders, cell death, organ dysfunction, and a series of clinicopathological symptoms.
Cuproptosis; Clinical diseases; Wilson’s disease; Menke’s disease
Wenxian An, Yaying Xie, Yuting Zhang. Research Progress on the Relationship between Cuproptosis and Clinical Related Diseases. Academic Journal of Medicine & Health Sciences (2023) Vol. 4, Issue 8: 76-80. https://doi.org/10.25236/AJMHS.2023.040813.
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