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International Journal of Frontiers in Medicine, 2023, 5(9); doi: 10.25236/IJFM.2023.050907.

Research Progress on MicroRNA in Early Diagnosis of Lung Cancer


Ruifei Yang1, Feixue Feng1, Yanxia Ma2

Corresponding Author:
Yanxia Ma

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Academy of Medical Technology, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China


Lung cancer is one of the most common and deadly types of cancer worldwide. Non-small cell lung cancer accounts for 85% of all lung cancers, and the survival rate of lung cancer patients is closely related to the time of diagnosis, with higher survival rates associated with early detection. However, early-stage lung cancer lacks specific clinical features, and most lung cancer patients do not exhibit obvious symptoms in the early stages of the disease. As a result, many patients are diagnosed in the intermediate or late stages. Pulmonary nodules are early manifestations of lung cancer, but not all nodules indicate lung cancer. With the advent of LDCT, more and more lung nodules are being detected, but distinguishing between benign and malignant nodules remains challenging. Therefore, there is an urgent need to develop blood-based biomarkers as more effective diagnostic tools for precise diagnosis of lung cancer in high-risk individuals.


Lung cancer; microRNA; biomarker; early diagnosis

Cite This Paper

Ruifei Yang, Feixue Feng, Yanxia Ma. Research Progress on MicroRNA in Early Diagnosis of Lung Cancer. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 9: 36-41. https://doi.org/10.25236/IJFM.2023.050907.


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