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Academic Journal of Agriculture & Life Sciences, 2023, 4(1); doi: 10.25236/AJALS.2023.040108.

Research progress in artificial gene circuit


Zeyue Yu

Corresponding Author:
Zeyue Yu

College of Life Sciences, Qingdao University, Qingdao, Shandong, 266071, China


A gene circuit is a genetic device consisting of gene regulatory elements and regulated genes. The basic theory of gene circuits includes the theory of synthetic biology and the regulation of gene expression. Gene circuits consist of logic gate gene circuits, bistable switches, and gene oscillators. The biggest challenge facing artificial gene circuits today is predictability. The behavior of artificial gene circuits within chassis cells may deviate from the predetermined behavior due to chassis-circuit coupling, the complexity of the circuits themselves, and other reasons. Rational design of gene circuits can be achieved by using mathematical modeling tools and computer support. Artificial gene circuits play an important role in chemical production, medical treatment, and life science research. This paper summarizes the knowledge about artificial gene circuits and describes the existing results and future developments in this field.


Synthetic Biology, Artificial Gene Circuits

Cite This Paper

Zeyue Yu. Research progress in artificial gene circuit. Academic Journal of Agriculture & Life Sciences (2023) Vol. 4 Issue 1: 54-61. https://doi.org/10.25236/AJALS.2023.040108.


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