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International Journal of Frontiers in Medicine, 2023, 5(11); doi: 10.25236/IJFM.2023.051106.

The Applications of Lactoferrin in Various Therapies and Nanotechnologies


Huang Jin1, Shi Lei1, Xia Ji2, Wang Nisha2, Ding Qiyang1, Yang Limei3, Lu Xiaohong4

Corresponding Author:
Lu Xiaohong

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Xi’an Jiaotong University, Xi'an, Shaanxi, 710049, China

3Yanliang People's Hospital, Xi'an, Shaanxi, 710089, China

4Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China


Lactoferrin (LF) is a natural glycoprotein that possesses iron-binding properties and multiple biological applications, including antiviral, anti-inflammatory, antioxidant, anticancer, and immunomodulatory effects. Due to the overexpression of LF receptors on many cells such as cancer cells and its ability to cross the blood-brain barrier (BBB), LF has demonstrated its potential for active targeting, making it an ideal nanocarrier for hydrophobic therapeutic agents. Therefore, LF, as a multifunctional protein, has shown broad prospects for application in cancer therapy and nanomedicine.


Lactoferrin; nanocarrier; brain targeting; cancer cell targeting

Cite This Paper

Huang Jin, Shi Lei, Xia Ji, Wang Nisha, Ding Qiyang, Yang Limei, Lu Xiaohong. The Applications of Lactoferrin in Various Therapies and Nanotechnologies. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 11: 39-45. https://doi.org/10.25236/IJFM.2023.051106.


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