This study aims to explore the effectiveness of the combination of nifedipine and low-dose aspirin in the treatment of patients with pregnancy induced hypertension. Pregnancy induced hypertension patients who underwent treatment in our hospital from September 2022 to September 2023 were selected as the research objects. According to the random number table method, a total of 96 patients were divided into a control group and an observation group, with 48 cases in each group. The control group was only treated with nifedipine, while the observation group was treated with nifedipine combined with low-dose aspirin. The therapeutic effects of the two groups were compared. Result: After treatment with nifedipine combined with low-dose aspirin, the blood pressure indicators, coagulation function indicators, vascular endothelial function indicators, peripheral blood inflammatory response indicators, incidence of adverse reactions, and incidence of adverse birth outcomes in newborns and postpartum women in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05). The combination of nifedipine and low-dose aspirin has an ideal therapeutic effect in the selection of treatment plans for patients with gestational hypertension, which can help maintain blood pressure stability and have a positive effect on the stability of their coagulation function and vascular endothelial function. At the same time, it can reduce peripheral inflammatory reactions, have high safety, and improve adverse outcomes for newborns and postpartum women.

Lingyan Zhang. Evaluation of the Efficacy of Nifedipine Combined with Low-dose Aspirin in the Treatment of Pregnancy Induced Hypertension. Academic Journal of Medicine & Health Sciences (2023) Vol. 4, Issue 12: 50-56. https://doi.org/10.25236/AJMHS.2023.041207.

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