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Academic Journal of Medicine & Health Sciences, 2023, 4(12); doi: 10.25236/AJMHS.2023.041215.

Research Progress of Exosomes in Parkinson's Disease


Xue Wenying1, Jia Ni2

Corresponding Author:
Jia Ni

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Department of Neurology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China


Exosomes are nano-vesicles secreted by cells, which can carry the transfer of intracellular protein and other substances. Parkinson's disease (PD) is one of the neurodegenerative diseases, characterized by the progressive loss of neurons, and the production of α -synuclein is its pathological marker. Studies have shown that during the onset of Parkinson's disease, exosomes mediate the toxic transmission of α -synuclein, which leads to the aggravation of the disease. At the same time, it can also be used as a potential biomarker for PD prodromal diagnosis and a potential drug carrier to help the early diagnosis and treatment of PD. This article will review the research progress of exosomes in the pathogenesis, diagnosis and treatment of PD, with a view to clinical application.


Exosomes; Parkinson's disease; Review

Cite This Paper

Xue Wenying, Jia Ni. Research Progress of Exosomes in Parkinson's Disease. Academic Journal of Medicine & Health Sciences (2023) Vol. 4, Issue 12: 110-115. https://doi.org/10.25236/AJMHS.2023.041215.


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