Intestinal mucus barrier is the first defense barrier, which can separate pathogenic bacteria from epithelial cells in the intestinal lumen and prevent some pathogenic substances from entering the human circulatory system through the intestinal barrier. Studies have shown that patients with functional constipation may have mucus barrier dysfunction and intestinal flora dysregulation, and the mechanism of the interaction between mucin 2 and intestinal flora on functional constipation is still unclear. Therefore, this paper reviewed the interaction mechanism between mucin 2 and intestinal flora, with a view to providing new ideas and directions for exploring the research related to functional constipation.

Kuang Mengfei, Liu Ya, Xu Dan, Jiang Hua. Exploring the mechanism of interaction between Muc2 and intestinal flora on functional constipation. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 12: 7-12. https://doi.org/10.25236/IJFM.2023.051202.

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