Welcome to Francis Academic Press

International Journal of Frontiers in Medicine, 2023, 5(12); doi: 10.25236/IJFM.2023.051208.

Progress in the Application of Chinese and Western Medicine in the Treatment of Chronic Osteomyelitis

Author(s)

Li Rui1, Cheng Yan2

Corresponding Author:
Cheng Yan
Affiliation(s)

1Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China

2Shaanxi Provincial Hospital of Chinese Medicine, Xi'an, Shaanxi, 710003, China

Abstract

Chronic osteomyelitis is a bone infection that occurs after open fracture or other bone and joint surgeries, and its treatment period is long, costly, recurrence rate is high, and the treatment is difficult, so it is extremely difficult to deal with. In recent years, with the improvement of academic and the introduction of new technologies, the treatment methods for chronic osteomyelitis have gradually increased, and its therapeutic effect has also been significantly improved. However, the treatment of chronic osteomyelitis by Western medicine still has some disadvantages, this article summarises the progress of clinical and experimental research on the treatment of chronic osteomyelitis by Chinese and Western medicine in recent years. It is found that chronic osteomyelitis is a combination of deficiency and solidity, and it is closely related to the internal organs, so the treatment should be based on the different stages of disease progression, and the treatment should be based on both attacking and supplementing, and the treatment should be based on both supporting the correctness of the disease and eliminating the evil spirits. Chinese medicine clinical practice includes Chinese medicine internal treatment, Chinese medicine external treatment and integrated therapy, Chinese medicine experimental research includes Chinese medicine anti-infection and Chinese medicine to promote bone formation, as well as the progress of experimental research on self-proposed prescriptions and empirical formulas, while Western medicine mainly treats chronic osteomyelitis from the aspects of antibiotic application, soft tissue defects and bone defects.

Keywords

Traditional Chinese medicine; western medicine; chronic osteomyelitis; progress in application

Cite This Paper

Li Rui, Cheng Yan. Progress in the Application of Chinese and Western Medicine in the Treatment of Chronic Osteomyelitis. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 12: 54-62. https://doi.org/10.25236/IJFM.2023.051208.

References

[1] Yi Guanhao, Han Ming. Research Progress on Traditional Chinese Medicine in the Treatment of Chronic Osteomyelitis [J]. Guangming Journal Of Chinese Medicine, 2023, 38(5):865-868. 

[2] Mitchell C. Birt, David W. Anderson, E. Bruce Toby, et al. Osteomyelitis: Recent advances in pathophysiology and therapeutic strategies [J]. Journal of Orthopaedics, 2017, 14(1):45-52.

[3] Wang Xiao, Tan Guoqing, Ma Chen, et al. Cao Yixun’s Experience in Treatment of Chronic Suppurative Osteomyelitis [J]. Shandong Journal of Traditional Chinese Medicine, 2021, 40(1):83-86.

[4] Tan JT, Wang Y. A summary of Wang Yong's experience in the treatment of chronic osteomyelitis by using Hu Xuan Zi Tang [J]. Shanxi Journal of Traditional Chinese Medicine, 2019, 35(10):4-5.

[5] Qin Daping, Zhang Xiaogang, Song Ming, et al. Discussion on TCM Treatment Strategy of Chronic Osteomyelitis from The Theory of Fuyang and nourishing Tendons [J]. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 2019, 25(8):1157-1160.

[6] Bai Haifeng, et al. Effectiveness Observation of Yanghe Decoction in Treatment of Patients with Traumatic Osteomyelitis [J]. Medical & Pharmaceutical Journal of Chinese People’s Liberation Army, 2019, 31(7):88-91.

[7] Su Jianguang. Clinical Effect of Modified Wuwei Disinfectant Soup in Treating Chronic Suppurative Osteomyelitis [J]. Journal of Mathematical Medicine, 2019, 32(3):416-417.

[8] Zhao Zejin, et al. Effect of Bone Fracture Restoring Decoction on Chronic Osteomyelitis of Tibia and Its Influence on Paley and HHS Score [J]. Liaoning Journal of Traditional Chinese Medicine, 2018, 45(7):1414-1417.

[9] Guo Zairan. Clinical observation on the treatment of chronic osteomyelitis of tibia bone (heat-toxicity embedded knot evidence) by external washing of traditional Chinese medicine [D]. Henan University of Traditional Chinese Medicine, 2016. 

[10] Qiang Shenglin, Song Pengcheng. Clinical observation on 23 cases of type II chronic osteomyelitis treated with de-tubularisation powder [J]. Journal of Gansu University of Chinese Medicine, 2017, 34(4):61-63.

[11] Zhang Yong, Wu Houxin, He Zhengbing. Clinical Study of Thunder Fire Moxibustion plus Implantation of Bone Cement Chain Beads Containing Antibiotics for Chronic Tibial Osteomyelitis [J]. Shanghai Journal of Acupuncture and Moxibustion, 2020, 39(10):1304-1308.

[12] Yin Fanbiao. Clinical effect of branding method combined with the addition and subtraction of Xianfang Livestrong Drink in the treatment of epiphyseal gangrene [J]. Henan Medical Research, 2020, 29(16):3020-3022.

[13] Chen Yingwen. Clinical efficacy of Lian Yin Tang combined with external application of traditional Chinese medicine in the treatment of traumatic septic osteomyelitis [J]. Chinese Journal of Clinical Rational Drug Use, 2018, 11(18):111-112.

[14] Wu Jiao, et al. Chemical Constituents and Pharmacological Effect of Lonicerae Japonicae Flos [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2019, 25(4):225-234.

[15] Zeng Shaoyang, Hu Wenbing, Li Hongzhi, et al. Influence on serum CRP, TNF-α and IL-6 with local treatment of bone cement beads contained Shuanghuanglian Fenzhenji in rabbits with chronic osteomyelitis [J]. Journal of Gansu University of Chinese Medicine, 2017, 34(2):1-6.

[16] Huang Xiaowen, et al. Protective Effect of Icariin on Lipopolysaccharide-induced Cytoskeleton F-actin Injury [J]. Chinese Journal of Modern Applied Pharmacy, 2019, 36(13):1612-1616.

[17] Ding Qiang, et al. Effect of glycoside of short-horned epimedium Herb on the expressions of transforming growth factorβ1 and basic fibroblast growth factor induced membrane by Masquelet technology [J]. Chinese Journal of Reparative and Reconstructive Surgery, 2020, 34(11):1405-1409.

[18] Liu Wei. Effects of total flavonoids of Boneset on the expression of Runx-2 in rat distraction osteogenesis model [D]. Changsha:Hunan University of Traditional Chinese Medicine, 2020. 

[19] Wang Jiang, Peng Liwei. Effects of sodium tanshinone IIA sulfonate on osteogenesis of rabbit mandibular distraction [J]. Chinese Remedies & Clinics, 2021, 21(10):1672-1673.

[20] Zhang Jun, et al. Experimental Study of Guyan Prescription on Chronic Osteomyelitis in Rabbits [J]. Chinese Journal of Traditional Medical Traumatology & Orthopedics, 2018, 26(9):14-18.

[21] Pan Xinwu. Experimental study on the efficacy of Chinese traditional medicine "Gangrene Spray" in rabbit chronic osteomyelitis model [D]. Gansu University of Traditional Chinese Medicine, 2018. 

[22] Li Dingpeng, Xie Xingwen, Pan Xingwu, et al. Mechanism of ADAMTS-7 and bone type I collagen expression in bone repair of rabbit osteomyelitis model[J]. Chinese Journal of Pharmacology and Toxicology [J]. Chinese Journal of Pharmacology and Toxicology, 2019, 33(10):836.

[23] Li Zhihong, et al. Observation on the Effect of Five-element Music Therapy in Patients of Chronic Osteomyelitis with Anxiety [J]. Guiding Journal of Traditional Chinese Medicine and Pharmacy, 2019, 25(16):72-74+78.

[24] Zhang Junling. Effect of auricular pressure bean with acupressure on preoperative symptoms of elevated blood pressure in patients with chronic osteomyelitis [J]. Biped and Health Care, 2018, 27(6):94-95.

[25] Peng Rao, Liao Tao, He Kaiyuan, et al. A study on the effect of time-selective acupoint massage method based on the theory of meridian flow injection on negative emotions of patients with qi and blood deficiency type of epiphyseal gangrene [J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2021, 30(12):1351-1355.

[26] Chi Taosheng, Wu Hongjun, Zhai Jianguo, et al. Analysis of bacterial drug sensitivity and resistance in traumatic osteomyelitis [J]. Chinese Journal of Traditional Medical Traumatology & Orthopedics, 2014, 22(2):52-53. 

[27] Yuan Weiqing, Zhou You, Yang Kun, et al. Research Progress in the Treatment of Chronic Osteomyelitis [J]. Popular Science & Technology, 2022, 24(271):106-109. 

[28] Li Hongchao. Clinical efficacy of antibiotic irrigation therapy combined with hyperbaric oxygen in the treatment of osteomyelitis [J]. Chinese Journal of Clinical Rational Drug Use, 2018, 11(36):79-80. 

[29] Chen Qin, Huang Kai. The one-stage surgical treatment of traumatic chronic osteomyelitis on the calcaneus [J]. Journal of Clinical Orthopaedics, 2016, 19(5):580-582. 

[30] Lin Peng, et al. Comparative Study of Modified Papineau Technique and Vancomycin Loaded Calcium Phosphate Topical Filling in the Treatment of Ceirny Type Ⅲ Osteomyelitis after Distraction Osteogenesis [J]. Progress in Modern Biomedicine, 2017, 17(13):2486-2490. 

[31] Jia Chao, et al. Masquelet technique for reconstruction of infected tibial defects with intramedullary nail in the second stage [J]. Journal of Regional Anatomy and Operative Surgery, 2020, 29(1):29-33. 

[32] Henrich D, Seebach C, Nau C, et al. Establishment and characterization of the Masquelet induced membrane technique in a rat femur critical-sized defect model [J]. Journal of tissue engineering and regenerative medicine, 2016, 10(10):E382-E396. 

[33] Liu Tao, Xie Bin, Miao Qiang, et al. Clinical Application Value of Vascularized Bone Graft in the Treatment of Bone Tumor of Extremities [J]. The Practical Journal of Cancer, 2017, 32(5):827-829. 

[34] He Guoyu, et al. Advantages and improvement strategies of Ilizarov technique in the treatment of tibial bone defect [J]. Chinese Journal of Tissue Engineering Research, 2020, 24(24):3870-3876. 

[35] Wang Danfeng, Sun Weidong. The Clinical Observation of Negative Pressure VSD in the Drainage of Chronic Osteomyelitis [J]. Guide of China Medicine, 2019, 17(35):163-165.