International Journal of Frontiers in Medicine, 2023, 5(12); doi: 10.25236/IJFM.2023.051214.
Qian Xu1, Tie Liu2, Haiyan Zhu1
1Department of Oncology, Weifang People's Hospital, Weifang, Shandong, 261041, China
2Department of Proctology, Weifang People's Hospital, Weifang, Shandong, 261041, China
Colorectal cancer is a malignant tumor with high incidence rate and mortality. Research has shown that the activation and inhibition of the Wnt signaling pathway are closely related to the occurrence and development of colorectal cancer, and the Wnt signaling pathway is influenced by many factors. Studying the relationship between the Wnt signaling pathway and the occurrence and development of colorectal cancer is beneficial for providing insights into the prevention and treatment of colorectal cancer. This article provides a review of the research progress on the relationship between the Wnt signaling pathway and the occurrence and development of colorectal cancer.
colorectal cancer, Wnt/ β- catenin signaling pathway, Research progress
Qian Xu, Tie Liu, Haiyan Zhu. Study on the occurrence and development of colorectal cancer. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 12: 94-97. https://doi.org/10.25236/IJFM.2023.051214.
[1] Shi Bin, Wang Jia, Ma Rong, etc NKD1 regulates Wnt/ β- mechanism of the influence of the catenin signaling pathway on the cell cycle of colorectal tumors [J]. Ningxia Medical Journal, 2023, 45 (05): 393-396+481+397. DOI: 10.13621/j.1001-5949.2023.05.0393
[2] Huang Renke, Ren Jianlin, Jing Lin, et al. Study on the Effect and Mechanism of Jianpi Tongluo Formula on Invasion and Migration of Colorectal Cancer Cells [J]. International Journal of Digestive Diseases, 2023, 43 (01): 39-47
[3] Wei Yujie, Zeng Jinhao, Zheng Qiao, et al. Targeted Traditional Chinese Medicine Research progress on the prevention and treatment of colorectal cancer through the Wnt/ β- catenin signaling pathway [J]. Pharmacology and Clinical Chinese Medicine, 2023, 39 (09): 117-123. DOI: 10.13412/j.cnki.zyyl. 20221119.001
[4] Si Xiaochuang. The expression and clinical significance of β- catenin, BRG1, and ADAM17 in colon cancer tissues [D]. North China University of Technology, 2022. DOI: 10.27108/dcnki. ghelu. 2022-000794
[5] Yang Binbin, Cui Ning, Zhang Yanan, etc. Based on research progress on traditional Chinese medicine intervention of the Wnt/ β- catenin signaling pathway in colorectal cancer [J]. Chinese Medical Journal, 2022, 19 (14): 32-35