International Journal of Frontiers in Medicine, 2024, 6(1); doi: 10.25236/IJFM.2024.060102.
He Fangzheng1,2, Gao Yuhao1,3, Liu Hualu1,3, Liao Changsheng1,2, Li Xiyong1,2, Han Pengfei1
1Orthopedics Department of Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, 046000, China
2Department of Graduate School, Graduate Student Department of Changzhi Medical College, Changzhi, Shanxi, 046000, China
3Changzhi Institute of Spinal Disease, Changzhi, Shanxi, 046000, China
The role of single-cell sequencing in degenerative diseases has attracted significant attention in current research. This study aims to investigate the global status and emerging trends in this field. The literature on single-cell sequencing in degenerative diseases was retrieved from January 1, 1991 to September 1, 2023, utilizing the Web of Science Citation Index Expanded. The source data was analyzed using bibliometric methods. To visualize the research findings, VOS viewer version 1.6.19 software was employed for co-authorship analysis, co-occurrence analysis, bibliographic coupling, and co-citation analysis. The study also evaluated the overall trend of single-cell sequencing in degenerative disease research in recent years. A total of 1430 articles were retrieved, reflecting a continuous increase in research and publications on single-cell sequencing in degenerative diseases worldwide. The United States has played a prominent role in this field, contributing the highest number of publications and citations, as well as having the highest h-index. Springer Nature and Frontiers Media Sa emerged as the leading publishers. Noteworthy contributors include the National Institutes of Health (NIH) in the USA, Nanjing Medical University, Harvard University, and the University of Texas System. The research in this field primarily focuses on three key aspects: oncology, genetics, and molecular biology. Oncology is predicted to be the next significant area of interest in single-cell sequencing research on degenerative diseases. The findings suggest that the number of publications related to single-cell sequencing in degenerative diseases will continue to increase based on current global research trends. Presently, the United States remains the primary driver of research in this field, with a focus on clinical studies, particularly in oncology, which is likely to become the next prominent topic in the realm of single-cell sequencing in degenerative diseases.
Single-Cell Sequencing, Degenerative Diseases, Global Trends, Bibliometrics, Visualization Research
He Fangzheng, Gao Yuhao, Liu Hualu, Liao Changsheng, Li Xiyong, Han Pengfei. Global Research Trends in Single-Cell Sequencing in Degenerative Disease Research: A Bibliometric and Visualization Study. International Journal of Frontiers in Medicine (2024), Vol. 6, Issue 1: 14-23. https://doi.org/10.25236/IJFM.2024.060102.
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