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International Journal of Frontiers in Medicine, 2020, 2(1); doi: 10.25236/IJFM.2020.020103.

Effect of pine needle extract on antioxidative ability of rats


Lin Chang 1, Ge Wu 1,Ting Li 1,Jiahui Zhang 1,Hongbo Wang 1,Qingping Xia2, *

Corresponding Author:
Qingping Xia

1. MuDanJiang  Medical  University,Mudanjiang  157011,China
2. Medicine Research Centre,MuDanJiang  Medical  University,Mudanjiang  157011,China
*Corresponding author e-mail:[email protected]


In order to explore the antioxidant capacity of pine needle extract, the scavenging capacity of free radicals in rat plasma was determined by pine needle proanthocyanidins extract, so as to preliminarily investigate the effect of pine needle extract on the antioxidant capacity of the body. 18 month old natural aging rats and 3 month old young rats were used as experimental animals. Randomly divided into blank control group, natural aging group, pine needle proanthocyanidins extract [1] gavage group. After 21 days of continuous administration, the eyeball was removed and the blood samples were collected. The contents of AOC, T-SOD and GSH were measured. By analyzing the different data of different groups, we can conclude the effect of pine needle extract on the antioxidant capacity of natural aging rats.


antioxidant capacity; pine needle extract; total superoxide dismutase (T-SOD); reduced glutathione (GSH)

Cite This Paper

Lin Chang, Ge Wu,Ting Li,Jiahui Zhang,Hongbo Wang,Qingping Xia. Effect of pine needle extract on antioxidative ability of rats. International Journal of Frontiers in Medicine (2020), Vol. 2, Issue 1: 18-24. https://doi.org/10.25236/IJFM.2020.020103.


[1] Zhang Guifang, Du Shanshan, Shi Rui, Li Bing, Zhang Dongjie. Effects of treatment methods and extraction solvents on antioxidant activity of pine needle extract [J]. Chinese Journal of hospital pharmacy, 2017, 37 (16): 1602-1606
[2] Xu Lishan, Zhang Haiwen. Antioxidant activity of pine needle extract [J]. Food science, 2011, (07): 97-99
[3] Liu JT. Oxygen free radical damage and antioxidants [J]. Physiology, 1988, (02): 83-84 + 90
[4] Hao Qinghong. Determination of the main components of Magnolia officinalis in scavenging oxygen free radicals and the anti-aging effect of magnolol [D]. Hebei Agricultural University, 2005
[5]Céspedes C L, Valdezmorales M, Avila J G, et al.Phytochemical profile and the antioxidant activity of Chileanwild black-berry fruits, Aristotelia chilensis (Mol) Stuntz(Elaeocarpaceae) [J]. Food Chemistry, 2010, 119(3): 886-895
[6] Yang Lihua. Study on antioxidant activity of Pinus massoniana Needles and development of antioxidant beverage [D]. Guangzhou Medical University, 2014
[7] Yang Kai. Health care application of pine needles and pine bark [J]. Guangdong science and technology, 2002, (11): 59-60
[8]Xue-Tong Wang,Jun Zhou,Bing-Li Lei,Jing-Ming Zhou,Si-Yue Xu,Bao-Ping Hu,De-Qing Wang,Dong-Ping Zhang,Ming-Hong Wu. Atmospheric occurrence, homologue patterns and source apportionment of short- and medium-chain chlorinated paraffins in Shanghai, China: Biomonitoring with Masson pine ( Pinus massoniana L.) needles[J]. Science of the Total Environment,2016,:.
[9] Dong Yiming, Dong Kan. Pine needle revolution [M]. Taiyuan: Shuhai press, 24.19
[10]Fernández-Varela R, Ratola N, Alves A, et al. Relationship between levels of polycyclic aromatic hydrocarbons in pine needles and socio-geographic parameters [J]. Journal of Environmental Management, 2015, 156: 52-61
[11] Li Qili. Study on the separation, component identification and antioxidant mechanism of oligoprocyanidins in Lotus peel [D]. Hunan Agricultural University, 2013
[12] Huang Qiliang. Preparation of Procyanidins from pine needles and Study on their main biological activities [D]. Zhejiang Normal University, 2012
[13] Wang Chunmei, Du xingxu. Antioxidant effect of pine needle extract on type Ⅱ diabetic rats [J]. Journal of Beihua University (NATURAL SCIENCE EDITION), 2013, (04): 426-428
[14] Diao Ling. Theoretical study on reaction mechanism of hydroxyl radical and nucleic acid base pair [D]. Shanghai University, 2015