International Journal of Frontiers in Medicine, 2020, 2(1); doi: 10.25236/IJFM.2020.020106.
Qingping Xia1, Shuihua Yan2,*, Chenning He2, Ge Wu2, Hui Shen 3
1. Medical Research Center,Mudanjiang Medical University, Mudanjiang 157011, China
2. College of pharmacy, Mudanjiang Medical University, Mudanjiang 157011, China
3. Institute of medical imaging,, Mudanjiang Medical University, Mudanjiang 157011, China
*Corresponding author e-mail: [email protected]
To investigate the effect of Acanthopanax senticosus extract on Spleen-yang deficiency and Kidney-yin deficiency in mice. Using the quantitative analysis method, it was found in the experiment that Acanthopanax senticosus extract can significantly reduce the β-EP content in the serum, and the reduction range increases and decreases with the increase and decrease of the dose. Acanthopanax senticosus extract can significantly increase the content of cAMP in the serum, and the effect of Acanthopanax senticosus extract on the kidney-yin deficiency group has a significant decrease in ACTH, CORT, CRH content. The results showed that the extract of Acanthopanax senticosus leaves had a regulating effect on spleen-yang deficiency and kidney-yin deficiency in mice.
Acanthopanax senticosus; Spleen-yang deficiency; Kidney-yin deficiency; β-EP; cAMP; CRH; CORT; ACTH
Qingping Xia, Shuihua Yan, Chenning He, Ge Wu, Hui Shen. Study on the Regulatory Effect of Acanthopanax senticosus Leaves Extract on Spleen-yang Deficiency and Kidney-yin Deficiency. International Journal of Frontiers in Medicine (2020), Vol. 2, Issue 1: 40-48. https://doi.org/10.25236/IJFM.2020.020106.
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