This review explores the health benefits of a traditional Chinese herbal tea blend comprising rose, mulberry fruit, Poria cocos (Fu Ling), lily (Bai He) and jujube, integrating both historical uses in traditional Chinese medicine and contemporary scientific research. Each ingredient has been selected for its unique properties and potential health benefits, which are examined through the lens of modern scientific evidence. We combine findings from various scientific studies, including clinical trials and pharmacological research, to substantiate the health claims associated with each herbal ingredient. This review aims to provide a comprehensive overview of the potential health benefits of this herbal tea blend, emphasizing the importance of integrating traditional knowledge with scientific research in the pursuit of natural health solutions. While promising, the review also acknowledges the need for further scientific studies to fully understand the mechanisms and long-term effects of these herbal ingredients on human health.

Yaoxu Zhou, Jiating Liang, Chengyong Wang, Rongting Ye. A Soothing Elixir: The Health Enhancing Qualities of a Unique Chinese Herbal Tea. Academic Journal of Agriculture & Life Sciences (2024) Vol. 5 Issue 1: 30-36. https://doi.org/10.25236/AJALS.2024.050105.

[1] Z. Yang, Y. Liu, Z. Song, Y. Fan, S. Lin, Z. Ge, S. Feng, Y. Liu, Y. Bi, Y. Wang, X. Wang, and J. Mao, Chinese patent medicines for coronary microvascular disease: clinical evidence and potential mechanisms. Int J Med Sci 20 (2023) 1024-1037.

[2] W. Zhuang, Z. Fan, Y. Chu, H. Wang, Y. Yang, L. Wu, N. Sun, G. Sun, Y. Shen, X. Lin, G. Guo, and S. Xi, Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China. Front Pharmacol 11 (2020) 1066.

[3] W. Zhuang, S.L. Liu, S.Y. Xi, Y.N. Feng, K. Wang, T. Abduwali, P. Liu, X.J. Zhou, L. Zhang, and X.Z. Dong, Traditional Chinese medicine decoctions and Chinese patent medicines for the treatment of depression: Efficacies and mechanisms. J Ethnopharmacol 307 (2023) 116272.

[4] C.N.P. Commission, Pharmacopoeia of the People's Republic of China :2005 edition, 2005.

[5] A.S. Hegde, S. Gupta, S. Sharma, V. Srivatsan, and P. Kumari, Edible rose flowers: A doorway to gastronomic and nutraceutical research. Food Res Int 162 (2022) 111977.

[6] H. Wang, Beneficial medicinal effects and material applications of rose. Heliyon 10 (2024) e23530.

[7] J. Shen, J. Shan, L. Zhong, B. Liang, D. Zhang, M. Li, and H. Tang, Dietary Phytochemicals that Can Extend Longevity by Regulation of Metabolism. Plant Foods Hum Nutr 77 (2022) 12-19.

[8] M.C. Dias, D. Pinto, and A.M.S. Silva, Plant Flavonoids: Chemical Characteristics and Biological Activity. Molecules 26 (2021).

[9] A. Kumar, N. P, M. Kumar, A. Jose, V. Tomer, E. Oz, C. Proestos, M. Zeng, T. Elobeid, S. K, and F. Oz, Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method. Molecules 28 (2023).

[10] T. Hongratanaworakit, Relaxing effect of rose oil on humans. Natural Product Communications 4 (2009) 291-296.

[11] D. Lee, J.S. Yu, S.R. Lee, G.S. Hwang, K.S. Kang, J.G. Park, H.Y. Kim, K.H. Kim, and N. Yamabe, Beneficial Effects of Bioactive Compounds in Mulberry Fruits against Cisplatin-Induced Nephrotoxicity. Int J Mol Sci 19 (2018).

[12] X. Li, Y. Hua, C. Yang, S. Liu, L. Tan, J. Guo, and Y. Li, Polysaccharides extracted from mulberry fruits (Morus nigra L.): antioxidant effect of ameliorating H(2)O(2)-induced liver injury in HepG2 cells. BMC Complement Med Ther 23 (2023) 112.

[13] J. Hao, Y. Gao, J. Xue, Y. Yang, J. Yin, T. Wu, and M. Zhang, Phytochemicals, Pharmacological Effects and Molecular Mechanisms of Mulberry. Foods 11 (2022).

[14] W. Wang, X. Li, X. Bao, L. Gao, and Y. Tao, Extraction of polysaccharides from black mulberry fruit and their effect on enhancing antioxidant activity. International Journal of Biological Macromolecules 120 (2018) 1420-1429.

[15] F. Yan, G. Dai, and X. Zheng, Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice. J Nutr Biochem 36 (2016) 68-80.

[16] W. Yihai, X. Limin, W. Chunhua, T. Chao, H. Xiangjiu, and P. Gianfranco, Antidiabetic and Antioxidant Effects and Phytochemicals of Mulberry Fruit (Morus alba L.) Polyphenol Enhanced Extract. Plos One 8 (2013) e71144.

[17] X. Chen, M.H. Sohouli, M. Nateghi, E. Melekoglu, and S. Fatahi, Impact of mulberry consumption on cardiometabolic risk factors: A systematic review and meta-analysis of randomized-controlled trials. J Clin Pharm Ther 47 (2022) 1982-1993.

[18] D.K. Yang, and D.G. Jo, Mulberry Fruit Extract Ameliorates Nonalcoholic Fatty Liver Disease (NAFLD) through Inhibition of Mitochondrial Oxidative Stress in Rats. Evidence-based Complementary and Alternative Medicine 2018 (2018) 1-9.

[19] H. Kim, H. Choi, B.G. Park, H.J. Ju, and Y.I. Kim, Efficacy of Poria Cocos Extract on Sleep Quality Enhancement: A Clinical Perspective with Implications for Functional Foods. Nutrients 15 (2023).

[20] C.Y.J. Ng, N.P.Y. Lai, W.M. Ng, K.T.H. Siah, R.Y. Gan, and L.L.D. Zhong, Chemical structures, extraction and analysis technologies, and bioactivities of edible fungal polysaccharides from Poria cocos: An updated review. Int J Biol Macromol 261 (2024) 129555.

[21] Y. Sun, Biological activities and potential health benefits of polysaccharides from Poria cocos and their derivatives. Int J Biol Macromol 68 (2014) 131-4.

[22] W. Li, J. Yu, J. Zhao, X. Xiao, W. Li, L. Zang, J. Yu, H. Liu, and X. Niu, Poria cocos polysaccharides reduces high-fat diet-induced arteriosclerosis in ApoE(-/-) mice by inhibiting inflammation. Phytother Res 35 (2021) 2220-2229.

[23] Y. Duan, J. Huang, M. Sun, Y. Jiang, S. Wang, L. Wang, N. Yu, D. Peng, Y. Wang, W. Chen, and Y. Zhang, Poria cocos polysaccharide improves intestinal barrier function and maintains intestinal homeostasis in mice. Int J Biol Macromol 249 (2023) 125953.

[24] X. Li, Y. He, P. Zeng, Y. Liu, M. Zhang, C. Hao, H. Wang, Z. Lv, and L. Zhang, Molecular basis for Poria cocos mushroom polysaccharide used as an antitumour drug in China. J Cell Mol Med 23 (2019) 4-20.

[25] L. Qin, D. Huang, J. Huang, F. Qin, and H. Huang, Integrated Analysis and Finding Reveal Anti-Liver Cancer Targets and Mechanisms of Pachyman (Poria cocos Polysaccharides). Front Pharmacol 12 (2021) 742349.

[26] Y. Lv, Y. Yang, Y. Chen, D. Wang, Y. Lei, M. Pan, Z. Wang, W. Xiao, and Y. Dai, Structural characterization and immunomodulatory activity of a water-soluble polysaccharide from Poria cocos. Int J Biol Macromol 261 (2024) 129878.

[27] P. Liu, Advances in chemical constituents and pharmacological effects of Lilium. Chinese Journal of Experimental Medicine 23 (2017) 11.

[28] L. Luo, G. Pei, L. Qin, X.J. Zhou, J. Zhan, N. Liao, and N. Chen, Research progress on chemical constituents and pharmacological effects of Lilium chinensis. New Chinese medicine and clinical pharmacology 028 (2017) 824-837.

[29] Q. Guo, Y. Gao, and w. Li, Effect of active part of lily on monoamine neurotransmitters in the brain of depression model rats. Chinese patent medicine 31 (2009) 4.

[30] Y. Lu, T. Bao, J. Mo, J. Ni, and W. Chen, Research advances in bioactive components and health benefits of jujube (Ziziphus jujuba Mill.) fruit. J Zhejiang Univ Sci B 22 (2021) 431-449.

[31] Y. Gu, J. Han, C. Jiang, and Y. Zhang, Biomarkers, oxidative stress and autophagy in skin aging. Ageing Res Rev 59 (2020) 101036.

[32] Y.R. Song, W.C. Lim, A. Han, M.H. Lee, E.J. Shin, K.M. Lee, T.G. Nam, and T.G. Lim, Rose Petal Extract (Rosa gallica) Exerts Skin Whitening and Anti-Skin Wrinkle Effects. J Med Food 23 (2020) 870-878.

[33] X. Yang, L. Yang, and H. Zheng, Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats. Food Chem Toxicol 48 (2010) 2374-9.

[34] C. Yang, T. Wang, Y. Zhao, X. Meng, W. Ding, Q. Wang, C. Liu, and H. Deng, Flavonoid 4,4'-dimethoxychalcone induced ferroptosis in cancer cells by synergistically activating Keap1/Nrf2/HMOX1 pathway and inhibiting FECH. Free Radic Biol Med 188 (2022) 14-23.

[35] P. Zhang, L. Fan, D. Zhang, Z. Zhang, and W. Wang, In Vitro Anti-Tumor and Hypoglycemic Effects of Total Flavonoids from Willow Buds. Molecules 28 (2023).