Mycoplasma pneumoniae pneumonia is more common in preschool and school-age children, and is mostly a benign and self-limiting disease. As the number of Mycoplasma pneumoniae infections in children continues to increase and the resistance of Mycoplasma pneumoniae to macrolide drugs increases, some children still show prolonged or recurrent symptoms after a certain course of anti -infection treatment, and even develop into severe Mycoplasma pneumoniae pneumonia, Seriously affecting children's physical health and quality of life. In recent years, research has found that traditional Chinese medicine (TCM) is suitable as an auxiliary treatment method for Mycoplasma pneumoniae pneumonia in children, which has the effect of promoting symptom relief and improving prognosis. This article provides a review of the epidemiological characteristics, etiology and pathogenesis of Mycoplasma pneumoniae pneumonia in children, as well as relevant traditional Chinese medicine appropriate techniques, in order to provide scientific basis for the clinical treatment and in-depth research of pediatric MPP using traditional Chinese medicine appropriate techniques.

Jiang Huangling, Zhao Jing, Sui Fuhui, Wang Jiamin. Research Progress of Traditional Chinese Medicine Appropriate Techniques for Mycoplasma Pneumoniae Pneumonia in Children. International Journal of Frontiers in Medicine (2024), Vol. 6, Issue 4: 1-8. https://doi.org/10.25236/IJFM.2024.060401.

[1] Tsai TA, Tsai CK, Kuo KC, et al. Rational stepwise approach for Mycoplasma pneumoniae pneumonia in children [J]. Microbiol Immunol Infect. 2021 Aug; 54(4):557-565.

[2] Su Jie, Wu Ting, Kuang Qi. Clinical study on the combination of Qingre Huatan Huoxue Fang and Azithromycin in the treatment of phlegm heat closed lung syndrome in children with Mycoplasma pneumonia [J]. New Traditional Chinese Medicine, 2023, 55 (23): 158-162.

[3] Hu Yan, Hao Jing, Yan Huimin. Integrated Traditional Chinese and Western Medicine Diagnosis and Treatment Plan for Mycoplasma Pneumonia in Children (2023 Edition) [J]. Beijing Traditional Chinese Medicine, 2023, 42 (11): 1175-1179.

[4] Cheng Y, Cheng Y, Dai S, et al. The Prevalence of Mycoplasma Pneumoniae among Children in Beijing before and During the COVID-19 Pandemic [J]. Front Cell Infect Microbiol. 2022 Apr 29;12: 854505. 

[5] Long Zhijian, Li Zhouyi, Liang Meijuan. Epidemiological characteristics of 1261 cases of Mycoplasma pneumoniae pneumonia in children [J]. Lingnan Journal of Emergency Medicine, 2022, 27 (04): 367-369.

[6] Wang Chunli, Sun Jinhan, Hei Zhiping. Clinical characteristics analysis of 989 cases of Mycoplasma pneumoniae infection in children [J]. Journal of Ningxia Medical University, 2023,45 (06): 612-618.

[7] Wu Qian, Wu Qiwu, Zhang Hailong, et al. Epidemic characteristics of Mycoplasma pneumoniae infection in children in Wuzhishan area and its correlation with climate factors [J]. Chinese Journal of Zoonozoonotic Diseases, 2019, 35 (07): 667-671.

[8] Cai Zhuang, Wang Xuefeng, Yang Jianshu. Professor Wang Xuefeng treats pneumonia wheeze from the perspective of lung and intestine based on the theory of treating visceral diseases [J]. Chinese Journal of Integrated Chinese and Western Pediatrics, 2023,15 (06): 500-503.

[9] Wang Xuefeng. Treatment of Severe Pediatric Pneumonia from the Perspective of Pulmonary Toxic Heat [J]. Journal of Traditional Chinese Medicine, 2012, 53 (03): 200-202.

[10] Shu Jing, Chen Fang, Yan Huimin. Theoretical exploration of traditional Chinese medicine syndrome characteristics of refractory Mycoplasma pneumoniae pneumonia in children [J]. Chinese Medicine Emergency, 2018, 27 (05): 871-873.

[11] Guan Zhiwei, Zhao Qiong, Ding Ying et al. Analysis of etiology and pathogenesis of mycoplasma pneumoniae pneumonia in children based on the theory of "warm pathogenic factors lead to rapid heat change" [J]. Shi Zhen Chinese Medicine, 2022,33(01):182-184.

[12] Yao Bo. Clinical study on the treatment of pediatric Mycoplasma pneumoniae pneumonia (phlegm heat closed lung syndrome) with Kaifei Xuanjiang Tang [D]. Changchun University of Traditional Chinese Medicine, 2022.

[13] Hu Yong, Yin Wenxue, Shu Kunpeng. The effect of modified Maxing Yinqiao powder combined with anti infection treatment on traditional Chinese medicine syndrome scores, T lymphocyte subsets, and prognosis in children with Mycoplasma pneumonia (wind heat closed lung type) [J]. Sichuan Traditional Chinese Medicine, 2023, 41 (11): 109-112.

[14] Gao Chao. Clinical observation of Qingfei Huatan Tang in the treatment of chronic cough caused by phlegm heat obstruction in the lungs after Mycoplasma pneumoniae infection in children [J]. Chinese Journal of Modern Distance Education in Traditional Chinese Medicine, 2023, 21 (14): 105-107.

[15] Liu Kexin, Zheng Ying, Zhang Xueli, et al. Clinical observation of heat sensitive moxibustion in the treatment of 80 cases of lung spleen deficiency type in the recovery period pneumonia wheeze[J]. Chinese Journal of Integrated Chinese and Western Medicine Pediatrics, 2021, 13 (05): 458-460.

[16] Yu Lingya, Shen Yanmei, Yuan Youdi. Observations on the therapeutic effect of point application of Penang Muxiang ointment on azithromycin induced gastrointestinal reactions [J]. Zhejiang Journal of Traditional Chinese Medicine, 2019, 54 (10): 728.

[17] Liu Yanling, Li Wenwen, Chen Hui. Clinical study on moxibustion hot compress to alleviate the side effects of intravenous infusion of azithromycin in children [J]. Journal of Traditional Chinese Medicine External Treatment, 2022, 31 (01): 52-53.

[18] Liu Yongtao, Wang Jihua, Jiang Jinxiang, et al. The therapeutic effect of moxibustion assisted sequential treatment with azithromycin on pediatric mycoplasma pneumonia and its impact on immune function [J]. Systems Medicine, 2023, 8 (18): 153-156.53

[19] Li Yanwei. Observation on the therapeutic effect of back acupoint cupping therapy on the absorption of rales in children with pneumonia [D]. Guangzhou University of Traditional Chinese Medicine, 2020.

[20] Jiang Yuxiu. Clinical observation on the treatment of pediatric pneumonia and wheezing with flash cupping method [J]. Modern Distance Education of Traditional Chinese Medicine in China, 2020, 18 (05): 119-120.

[21] Li Runhua, Yan Zhiqing, You Queping. The effect of silicone scraping on the treatment of pediatric mycoplasma pneumonia with phlegm heat closed lung type [J]. Huaxia Medical Journal, 2023, 36 (01): 88-91.

[22] Zhang Ningning, Wu Liqun, Liao Xinting et al. Study on the effect of bladder meridian scraping on the sustained antipyretic effect and endogenous pyrogen levels in children with pneumonia fever [J]. Journal of Modern Integrated Chinese and Western Medicine, 2021, 30 (32): 3576-3580.

[23] Li Wen, Wu Wenhua, Jiang Zhiyan, et al. Observation of the therapeutic effect of pediatric tuina therapy on chronic cough after pneumonia caused by Mycoplasma pneumoniae infection in children with phlegm dampness accumulation lung type [J]. Chinese Journal of Basic Medicine of Traditional Chinese Medicine, 2019, 25 (05): 645-647+709.

[24] Wan Xin. Observation on the therapeutic effect of sequential treatment of Mycoplasma pneumoniae pneumonia with pediatric massage combined with azithromycin [J]. Yunnan Journal of Traditional Chinese Medicine, 2022, 43 (02): 68-70.

[25] Fu Ouli. Clinical observation on the therapeutic effect of Shanghai style pediatric tuina in treating asthma caused by phlegm heat closed lung pneumonia [D]. Shanghai University of Traditional Chinese Medicine, 2023.

[26] Zhao Juanping, Zhang Qiuyue, Qi Xiao et al. Research overview of traditional Chinese medicine acupoint application in the treatment of respiratory system diseases [J]. Chinese Journal of Traditional Chinese Medicine, 2017, 35 (07): 1780-1783.

[27] Sun Yingxue, Liu Weiran. Clinical observation of traditional Chinese medicine syndrome differentiation acupoint application therapy as an auxiliary treatment for childhood Mycoplasma pneumonia [J]. World Journal of Integrated Chinese and Western Medicine, 2022, 17 (05): 978-981 +986.

[28] Tan Chunfeng, Huo Hongmei, Liu Jianhao, etc. Observation on the efficacy of acupoint application in the treatment of mycoplasma pneumonia in children and its effect on serum inflammatory factors and immune function [J]. Shanghai Journal of acupuncture and moxibustion, 2021,40 (09): 1053-1058.

[29] Wang Lixia. Analysis of the effect of ear acupoint pressing beans combined with azithromycin in the treatment of pediatric mycoplasma pneumonia [J]. Contemporary Nurses (Second Half), 2018,25 (07): 87-88.

[30] Wang Yalei, Li Chenshuai, Zhang Yana. Clinical observation of Huagai San decoction rectal push method in the treatment of pediatric pneumonia asthma (wind cold closed lung) [J]. Guangming Traditional Chinese Medicine, 2020,35 (16): 2474-2476.

[31] Ma Chun, Wang Jialin, Xu Ziyao et al. Meta analysis of the effectiveness and safety of traditional Chinese medicine enema in the treatment of pediatric pneumonia [J]. Chinese Journal of Sanatorium Medicine, 2023,32 (07): 679-684.

[32] Zhai Xiaohui, Xu Yuying. Clinical observation of moxibustion combined with acupoint application in the treatment of pediatric Mycoplasma pneumonia wind cold closed lung type [J]. Chinese Folk Therapy, 2019,27 (19): 88-89+105.

[33] Fu Yan. Value exploration of modified Ma Xing Yin Qiao San combined with meridian massage in the treatment of pediatric pneumonia wheeze(wind heat closed lung syndrome) [J]. Chinese Medical Innovation, 2023,20 (09): 32-35.