Hepatocellular carcinoma (HCC) is a common malignant tumor. Apoptosis and autophagy play an important role in the occurrence and development of HCC.It has been found that there is an interaction between apoptosis and autophagy in the treatment of hepatocellular carcinoma. Apoptosis is one of the main ways of cell death in hepatocellular carcinoma. Cell autophagy in hepatocellular carcinoma has a bilateral role of protective autophagy and lethal autophagy. Apoptosis is one of the main ways of cell death in hepatocellular carcinoma. Cell autophagy in hepatocellular carcinoma has a bilateral role of protective autophagy and lethal autophagy. Protective autophagy can inhibit the apoptosis of liver cancer cells induced by anticancer drugs, while lethal autophagy can induce the death of liver cancer cells in cooperation with apoptosis. Therefore, clarifying the interaction between apoptosis and autophagy in liver cancer will help to improve the efficacy of anti-tumor drugs in the clinical treatment of liver cancer. This article mainly discusses the relationship between hepatocellular carcinoma cell apoptosis and autophagy and its related influencing factors.

Wang Xiaofeng, Gou Yulei, Chu Jingli, Li Tao, Shi Xiaoyan, Li Cuijuan, Guo Dongyan, Fan Yu. Research Progress in the Mechanism of Apoptosis and Autophagy on Hepatocarcinogenesis. Academic Journal of Medicine & Health Sciences (2024), Vol. 5, Issue 9: 1-5. https://doi.org/10.25236/AJMHS.2024.050901.

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