To investigate the effect of pulmonary rehabilitation training combined with non-invasive ventilator in elderly patients with acute exacerbation of COPD complicated with respiratory failure. 80 elderly patients with acute exacerbation of COPD combined with respiratory failure (January 2023 to December 2023) were selected and grouped by random number table method. Control group (40 cases) received conventional treatment plus noninvasive ventilator treatment. The study group (40 cases) carried out pulmonary rehabilitation training on the basis of the control group. The therapeutic effect, lung function, blood gas index, cardiopulmonary oxygenation index, inflammatory factors, respiratory rate and heart rate were compared. The effective rate of study group was higher than that of control group (P < 0.05). After treatment, the proportion of forced vital capacity, first second expiratory volume and first second expiratory volume in forced vital capacity in the study group was higher than that in the control group (P < 0.05). After treatment, the partial pressure of arterial blood oxygen and saturation of blood oxygen in the study group were higher than those in the control group, and the fraction of arterial blood carbon dioxide was lower than that in the control group (P < 0.05). After treatment, the maximal oxygen uptake and consumption metabolic equivalent of the study group were higher than those of the control group (P < 0.05). The levels of C-reactive protein and procalcitonin in the study group after treatment were lower than those in the control group (P < 0.05). After treatment, the respiratory rate and heart rate of the study group were lower than those of the control group (P < 0.05). The combination of pulmonary rehabilitation training and non-invasive ventilator in the clinical treatment of acute COPD exacerbation with respiratory failure in the elderly has good therapeutic effect, and can improve lung function, blood gas index, cardiopulmonary oxygenation index, inflammatory factors, respiratory rate and heart rate.

Junting Ma, Xiaorong Xu, Yan Gao, Jingjing Niu. Effect of Pulmonary Rehabilitation Training Combined with Non-invasive Ventilator on Elderly Patients with Acute Exacerbation of COPD Complicated with Respiratory Failure. Academic Journal of Medicine & Health Sciences (2024), Vol. 5, Issue 10: 33-38. https://doi.org/10.25236/AJMHS.2024.051006.

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