Anorectal diseases, as common diseases, often lead to patients' delayed medical treatment due to hidden location. With the development of the disease, most patients need surgical operations. However, due to the special anatomical structure of the anus and the distribution of a large number of sensitive nerves around the anus, patients often suffer from severe pain due to postoperative defecation treatment and other stimulation, and the long course of the disease is not conducive to wound healing, so the pain intervention is particularly important. The application of traditional Chinese medicine characteristic technology based on the idea of prevention before disease in advance analgesia in anorectal surgery can not only better reduce pain and speed up the recovery of patients, but also have more diversified ways, more targeted, and higher patient compliance, so as to achieve the purpose of prevention before pain. This paper reviews the application of traditional Chinese medicine characteristic technology based on the idea of preventing diseases before they are diagnosed in advance analgesia in anorectal surgery, and summarizes and analyzes its mechanism, application, advantages, etc., in order to provide some reference for clinical practice when patients have pain intervention in anorectal surgery.

Cao Li, Hao Yuying, Zhang Xiao, Liu Jie, Song Rui. Application of traditional Chinese medicine characteristic technique in prevention of anorectal operation without pain. Academic Journal of Medicine & Health Sciences (2025), Vol. 6, Issue 1: 9-14. https://doi.org/10.25236/AJMHS.2025.060102.

[1] Cheng Y L, Wu Y L, Li W L, et al. Progress of epidemiological investigation of anorectal diseases in China[J]. Chinese Journal of Anorectal Diseases, 2022,42(06): 74-76.

[2] Liu Q R, Dai Y C, Ji M H, et al. Predictors and predictive effects of acute pain trajectories after  gastrointestinal surgery[J]. Sci Rep, 2022,12(1): 6530.

[3] Deshler B J, Rockenbach E, Patel T, et al. Current update on multimodal analgesia and nonopiate surgical pain management[J]. Curr Probl Surg, 2023,60(6).

[4] Pirie K, Traer E, Finniss D, et al. Current approaches to acute postoperative pain management after major abdominal  surgery: a narrative review and future directions[J]. Br J Anaesth, 2022,129(3): 378-393.

[5] Baldo B A. Toxicities of opioid analgesics: respiratory depression, histamine release,  hemodynamic changes, hypersensitivity, serotonin toxicity[J]. Arch Toxicol, 2021,95(8): 2627-2642.

[6] Chow S L, Sasson C, Benjamin I J, et al. Opioid Use and Its Relationship to Cardiovascular Disease and Brain Health: A  Presidential Advisory From the American Heart Association[J]. Circulation, 2021, 144(13): e218-e232.

[7] Zheng J. Application and research progress of preemptive analgesia in anesthesia [J]. Journal of Contemporary Medicine,2018,16(10):59-60. 

[8] Xuan C, Yan W, Wang D, et al. Efficacy of preemptive analgesia treatments for the management of postoperative  pain: a network meta-analysis[J]. Br J Anaesth, 2022,129(6): 946-958.

[9] Xia Y X, Qiao Y J, Li D D, et al. Research progress on the application of preemptive analgesia[J]. Nursing Research, 2022,36(10): 1831-1834.

[10] Kazachenko E, Garmanova T, Derinov A, et al. Preemptive analgesia for hemorrhoidectomy: study protocol for a prospective,  randomized, double-blind trial[J]. Trials, 2022,23(1): 536.

[11] Deng Y N, Pan X N, Liu X, et al. Comparison of acupuncture and lumbar plexus block in preemptive analgesia in patients with total hip replacement[J]. Shaanxi traditional Chinese medicine, 2022,43(10): 1455-1458.

[12] Ge Z, Li M, Chen Y, et al. The Efficacy and Safety of Parecoxib Multimodal Preemptive Analgesia in  Artificial Joint Replacement: A Systematic Review and Meta-Analysis of Randomized  Controlled Trials[J]. Pain Ther, 2023,12(4): 1065-1078.

[13] Woolf C J. Evidence for a central component of post-injury pain hypersensitivity[J]. Nature, 1983,306(5944): 686-688.

[14] Zhang Q, Zhou M, Huo M, et al. Mechanisms of acupuncture-electroacupuncture on inflammatory pain[J]. Mol Pain, 2023,19: 814404162.

[15] Zhao Y, Zheng J G, Lu M D, et al. Effect of electroacupuncture preemptive analgesia on activation of spinal dorsal horn neurons and astrocytes[J]. Journal of Modern Chinese and Western Integrative Medicine, 2020,29(18): 1957-1962.

[16] Liu Q, Liu Y, Bian J, et al. The preemptive analgesia of pre-electroacupuncture in rats with formalin-induced  acute inflammatory pain[J]. Mol Pain, 2019,15: 2069296991.

[17] Yan X B, Han X CH, Xing Q ZH, et al. Comparative study of electroacupuncture internal acupoint and Neiguan point and epidural nerve block in advanced analgesia in thoracic surgery patients[J]. Chinese acupuncture, 2021,41(01): 59-64.

[18] Yan X B, Han X C, Xing Q Z, et al. [Comparative study between electroacupuncture at Neima point and Neiguan (PC 6)  and epidural nerve block for preemptive analgesia in patients undergoing thoracic  surgery][J]. Zhongguo Zhen Jiu, 2021,41(1): 59-64.

[19] Xu N, Jiang K, Liu L, et al. Effect of intracutaneous pyonex therapy on postoperative pain management following perianal surgery: A systematic review and meta-analysis[J]. PLoS One, 2024,19(1): e0296439.

[20] Xiang J Y, Wu L, Chen B H. Effect of electroacupuncture combined with Parecoxib sodium on postoperative pain in patients with mixed hemorrhoids[J]. Traditional Chinese medicine in western China, 2019,32(05): 120-122.

[21] Song Y Y, Ni G X. Effect of preoperative intervention of electroacupuncture at Baliao point on  postoperative complications of procedure for prolapsed and hemorrhoids[J]. Zhongguo Zhen Jiu, 2019,39(3): 253-256.

[22] Li L, Tang Y, Ge W, et al. Effect of prescient analgesia on pain and serum PGE_2 after hemorrhoidal surgery[J]. Practical clinical integration of traditional Chinese and Western medicine, 2021,21(19): 39-41.

[23] Sun ZH R, J  K P, C G F, et al. Discussion on Traditional Chinese medicine "Treating no disease" from acupuncture pretreatment[J]. Chinese Journal of Traditional Chinese Medicine, 2020,35(03): 1078-1081.

[24] Lu S, Wang B, Wang J, et al. Moxibustion for the Treatment of Cancer and its Complications: Efficacies and  Mechanisms[J]. Integr Cancer Ther, 2023,22: 1563513225.

[25] Li X H, Sun X X, Liang Y L, et al. Effects of moxibustion at different times on Prostaglandin and vasopressin Contents in Uterine Tissue of cold-dampness and Stagnation dysmenorrhea rats[J]. J Acupunct Tuina Sci, 2017,15(04): 250-256.

[26] Qu Y H. Study on the effect of advanced intervention of Traditional Chinese Medicine Nursing Technology on postoperative pain of Hemorrhoids patients [C]. 2014 Anorectal Branch Annual Meeting, Chengdu, Sichuan, China, 2014. 

[27] Yang W W, Chen P B, Jin M, et al. Effect of proximal and distal acupoint embedding on uterine prostaglandin, serum IL-2 and spleen NK cells in primary dysmenorrhea rats[J]. Acupuncture study, 2021,46(03): 221-225.

[28] Chen P B, Chen J, Cui J, et al. Regulation and effect of acupoint embedding method on neuroendocrine-immune network in primary dysmenorrhea rats[J]. Acupuncture study, 2018,43(01): 29-33.

[29] Zhang S F, Zhao  J N, Yuan D H, et al. Effect of pre-emptive analgesia on β-endorphin and nitric oxide after operation of anal disease[J]. New traditional Chinese medicine, 2010,42(12): 104-106.

[30] Tang H L, Zheng D, Wang Y Y, et al. Clinical effect of acupoint catenary embedding in the prevention and treatment of postoperative pain of mixed hemorrhoids[J]. Journal of Shanghai University of Traditional Chinese Medicine, 2022,36(04): 36-40.

[31] Huang CH Z, Li Y L, Lan X L, et al. Effect of electroacupuncture combined with acupoint embedding on pain degree of patients after anal fistula incision[J]. Acupuncture study, 2021,46(05): 421-425.

[32] Wang Y Ch, Mo J, Li L, et al. The theoretical origin and clinical application of auricular acupoint cutting therapy[J]. Zhejiang Journal of Traditional Chinese Medicine, 2021,56(08): 622-623.

[33] Zhou M, Ding X F, Xie B,et al. Application of earpoint prescient analgesia in daytime hemorrhoidal surgery [J]. Journal of Famous Medicine,2023,(15):147-149. 

[34] Huang D. Effects of Intraoperative acupressure on pain and negative emotions of patients undergoing hemorrhoid surgery[J]. New traditional Chinese medicine, 2016,48(10): 209-211.

[35] Li Y Y. Effect of acupoint injection of dezocine on postoperative pain of mixed hemorrhoids[J]. Qinghai Medical Journal, 2017,47(06): 19-20.