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International Journal of Frontiers in Medicine, 2025, 7(1); doi: 10.25236/IJFM.2025.070109.

Adult Lumbar Langerhans Cell Histiocytosis: A Case Report

Author(s)

Yiwen Xu1, Jie Huang1, Hao Huang1, Ze Gao1, Xinhui Chi1, Zijian Cheng2, Mingxie Chen3, Jing Wang1

Corresponding Author:
Jing Wang
Affiliation(s)

1The First Affiliated Hospital of Jinan University, Guangzhou, 510623, China

2School of Basic Medical Sciences, Jinan University, Guangzhou, 510623, China

3Dongguan Tungwah Hospital, Dongguan, 523120, China

Abstract

Langerhans cell histiocytosis (LCH) is an extremely rare inflammatory myeloid tumor disease. This article reports a 25-year-old male patient who sought medical attention for one month due to persistent lower back pain. Imaging examination suggests the possibility of tumor like lesions in the L3 vertebral body, which was ultimately diagnosed as LCH through surgical pathological biopsy. This case can provide important reference for clinical doctors and other frontline medical personnel, enrich the existing knowledge base of adult lumbar LCH, improve understanding of the disease, and reduce misdiagnosis rate.

Keywords

Langerhans cell histiocytosis, adult spine, osteolytic lesions, surgical treatment

Cite This Paper

Yiwen Xu, Jie Huang, Hao Huang, Ze Gao, Xinhui Chi, Zijian Cheng, Mingxie Chen, Jing Wang. Adult Lumbar Langerhans Cell Histiocytosis: A Case Report. International Journal of Frontiers in Medicine (2025), Vol. 7, Issue 1: 56-63. https://doi.org/10.25236/IJFM.2025.070109.

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