Migrants to high-altitude regions face multi-system health risks but lack comprehensive assessment tools. This study developed the "Plateau Multidimensional Health Questionnaire" and surveyed 1237 migrants in plateau region (male 74.8%, female 25.2%; age 22.35 ± 6.51 years). Exploratory factor analysis identified five factors: Digestive-Autonomic Nervous Dysfunction (F1, variance 12.53%), Abnormal Thermoregulation (F2), Skin Metabolism Abnormalities (F3), Immune-Inflammatory Response (F4) , and Endocrine Imbalance (F5) ,which collectively explained 53.47% of the variance (Cronbach's α = 0.708). The results showed: F1 was significantly positively correlated with F2-F5 (r = 0.287–0.379, p < 0.01), suggesting a pivotal role of autonomic regulation in multi-system comorbidity. Female participants scored significantly higher than males on F1-F3 (p < 0.01), which may be related to estrogen-immune interactions. The group aged ≥31 years had higher incidence of F1/F4, while the 20-25 years group had a prominent F3, reflecting age-specific exposure risks. This study provides the first multidimensional assessment framework for plateau health management, with future research needed to validate these findings using longitudinal data.

Yifan Wu. Development of the Plateau Multidimensional Health Questionnaire. Academic Journal of Medicine & Health Sciences(2025), Vol. 6, Issue 3: 25-31. https://doi.org/10.25236/AJMHS.2025.060305.

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