In this paper, we would like to investigate the efficacy of acupuncture warm moxibustion and gua sha in treating Parkinson's disease qi deficiency constipation, the study subjects were 80 patients with Parkinson's disease qi deficiency constipation patients who visited Xi'an Traditional Chinese Medicine Hospital from February 2022 to February 2023, and were randomly divided into the control group and the experimental group of 40 cases each, the patients in the control group were given oral marengine soft capsules, and the experimental group was implemented with acupuncture warm moxibustion and gua sha therapy, and we compared the Bristol Stooliness Scale (BSFS), Chronic Constipation Severity Scale (CSS), and Constipation Quality of Life Scale (PAC-QOL) scores were compared between the two groups. The results suggest that, compared with the pre-treatment, the CSS score and PAC-QOL score of the two groups of patients decreased significantly after treatment, and the BSFS score improved significantly, and the difference was statistically significant (P < 0.001), and the efficacy of the experimental group after treatment was 95%, which was higher than that of the control group, which was 82.5%, and the difference was statistically significant (P < 0.05). It indicates that acupuncture stone warm moxibustion scraping therapy can effectively improve the constipation symptoms and quality of life of patients with Parkinson's disease qi deficiency constipation, the efficacy is better, and it is worthy of clinical promotion and application.

Zhou Yingying, Nie Ya'e, Qu Yan, Fan Yaxin, Ma Minghui. Observation on the effect of acupuncture warm moxibustion and gua sha in the treatment of constipation in Parkinson's disease with qi deficiency. Academic Journal of Medicine & Health Sciences(2025), Vol. 6, Issue 4: 46-53. https://doi.org/10.25236/AJMHS.2025.060408.

[1] Barnett R. Parkinson's disease[J]. Lancet, 2016,387(10015):217.

[2] Han M N, Finkelstein D I, McQuade R M, et al. Gastrointestinal Dysfunction in Parkinson's Disease: Current and Potential Therapeutics[J]. J Pers Med, 2022,12(2).

[3] ZHANG Tianqing, SHI Jing, LI Ting, et al. Chinese medicine symptoms of Parkinson's disease combined with functional constipation[J]. Journal of Traditional Chinese Medicine, 2019,60(06):518-521.

[4] LU Lu, YUAN Xiaolei, ZHANG Yan, et al. The relationship between constipation and motor symptoms and the distribution of Chinese medicine patterns in Parkinson's patients[J]. Journal of Cardiovascular and Cerebrovascular Diseases, 2019,17(21):3299-3303.

[5] Stocchi F, Torti M. Constipation in Parkinson's Disease[J]. Int Rev Neurobiol, 2017,134:811-826.

[6] SHI Tiantian, FENG Haixia. Survey on the current situation of functional constipation among the elderly in nursing institutions and analysis of influencing factors[J]. Contemporary Nurses (Lower Decade)), 2024,31(11):108-111.

[7] GOLDEN WON, LEI LONG-MING, SHEN YAN-MAO, et al. Application of acupressure in the care of constipation in patients with acute low back pain disease[J]. Nursing Research, 2016,30(27):3386-3388.

[8] LU Chunhua, ZHANG Huamei, ZHENG Fang, et al. Clinical observation of deep stabbing at Tianshu point on post-stroke constipation and its modulating effect on serum SP and VIP[J]. World Science and Technology-Modernization of Traditional Chinese Medicine, 2020,22(06):2000-2005.

[9] YU Qiang, LIU Wei, JIANG Jing, et al. Experimental study on the effects of different laxatives on colonic melanosis in guinea pigs[J]. Journal of Beijing University of Chinese Medicine, 2018,41(01):53-59.

[10] BAO Ruifang, CHEN Yunjing, MA Junrui, et al. Current status of the application of external treatment of Chinese medicine in patients with constipation in coronary heart disease[J]. China Clinical Nursing, 2024,16(04):247-250.

[11] Zou Xiumei, Duan Xiaoyan, Jia Ni, et al. Efficacy of hot ironing with Chinese medicine acupuncture stone in the treatment of constipation in Parkinson's disease with Qi deficiency[J]. World Science and Technology - Modernization of Traditional Chinese Medicine, 2022,24(11):4620-4626.

[12] Chen YP, Shang HF. 2016 Interpretation of Chinese diagnostic criteria for Parkinson's disease[J]. Chinese Journal of Practical Internal Medicine, 2017,37(02):124-126.

[13] Gastrointestinal Dynamics Group of the Chinese Society of Gastroenterology Chinese Society of Surgery Colorectal and Anal Surgery Group of the Chinese Medical Association. Guidelines for the diagnosis and treatment of chronic constipation in China.(2013, Wuhan)[J]. Gastroenterology, 2013,18(10):605-612.

[14] SHEN Hong, ZHANG Lu, YE Bai. Expert consensus opinion on Chinese medicine diagnosis and treatment of constipation (2017)[J]. Beijing Traditional Chinese Medicine, 2017,36(09):771-776.

[15] JING Tingting, LI Rui, WANG Dan, et al. Effect of acupoint massage and traditional Chinese medicine hot compresses on constipated patients with diabetic nephropathy under the guidance of the theory of meridian flow injection[J]. Medical Theory and Practice, 2023,36(24):4303-4305.

[16] Xie Suping, Yu Liqin. Recent research advances in the care of elderly patients with Parkinson's disease combined with depression[J]. World Abstracts of Recent Medical Information, 2019,19(10):29-30.

[17] Lewis S J, Heaton K W. Stool form scale as a useful guide to intestinal transit time[J]. Scand J Gastroenterol, 1997,32(9):920-924.

[18] Agachan F, Chen T, Pfeifer J, et al. A constipation scoring system to simplify evaluation and management of constipated patients[J]. Dis Colon Rectum, 1996,39(6):681-685.

[19] WANG Haibao, WANG Liang, ZHANG Hongmei. Research progress of self-assessment tool for constipation symptoms[J]. China Clinical Nursing, 2019,11(05):452-456.

[20] Marquis P, De La Loge C, Dubois D, et al. Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire[J]. Scand J Gastroenterol, 2005,40(5):540-551.

[21] State Administration of Traditional Chinese Medicine. Diagnostic and therapeutic efficacy standards of Chinese medicine [M]. Nanjing: Nanjing University Press, 1994.

[22] Li Tonggang. Progress of Chinese medicine understanding and treatment of constipation in Parkinson's disease[J]. Geriatrics Research, 2022,3(06):58-61.

[23] ZHAO Lili, GAO Jian, ZHANG Shuo, et al. Changes in serum inflammatory factors IL-6, IL-1β and IL-17 in Parkinson's disease patients with antecedent constipation and their clinical significance[J]. Chinese Journal of Gerontology, 2024,44(04):845-847.

[24] ZHAO Dana, YU Mingzhu, YANG Aiyang, et al. Therapeutic effect of acupuncture and meridian massage combined with biofeedback in the treatment of spleen and kidney yang deficiency-type constipation with outlet obstruction[J]. Nursing Research, 2023,37(18):3404-3407.

[25] Cai YuXuan. Study on the Selection Laws of Acupuncture and Moxibustion for Bidirectional Regulation of the Intestinal Tract in Contemporary Literature Based on Data Mining [D]. Nanjing University of Traditional Chinese Medicine, 2019.

[26] ZHANG Zhilong, JI Xuequn, ZHAO Shuhua, et al. A multicenter randomized controlled study of electroacupuncture at Zhigou acupoint for the treatment of qi secret of constipation[J]. Chinese Acupuncture and Moxibustion, 2007(07):475-478.

[27] Ivana Ye, Shuqin Pang, Yulan Ding, et al. Effectiveness of acupuncture point massage in preventing constipation after posterior lumbar interbody fusion[J]. Nursing Research, 2020, 34(02):347-350.

[28] XU Aili, LI Yuan, YANG Jianqin, et al. Research progress of Tianshu and Shangjiuxu as basic acupoints for the treatment of gastrointestinal diseases[J]. World Traditional Chinese Medicine, 2022,17(21):3096-3100.

[29] SUN Yonghui, ZHAO Zhenshuan, SUN Yanhui, et al. Clinical observation on the treatment of constipation after chemotherapy with vincristine in combination with mangosteen acupuncture and warm acupuncture[J]. Shanxi Medical Journal, 2016,45(05):551-552.

[30] YUAN Ting, WANG Zhenguo. A preliminary study on the origin of ancient stone therapy under the vision of cultural system[J]. World Science and Technology - Modernization of Traditional Chinese Medicine, 2015,17(12):2502-2507.

[31] Wu, Yi-Yin. Research on the heat transfer performance and clinical application of stone warming method in simulated human body [D]. Guangzhou University of Traditional Chinese Medicine, 2017.

[32] Si Wu,Chen Xiuhua. Exploration of the mechanism of action of Sibin stone[C]//Proceedings of the 2016 Academic Annual Meeting of the Chinese Acupuncture and Moxibustion Society Acupuncture and Gua Sha Professional Committee.2016 Chinese Acupuncture and Moxibustion Society Acupuncture and Gua Sha Professional Committee Academic Annual Meeting. The Second Clinical Medical College of Guangzhou University of Traditional Chinese Medicine;,2016:93-95.

[33] Lin L, Cheng K, Tan M T, et al. Comparison of the effects of 10.6-mum infrared laser and traditional moxibustion in the treatment of knee osteoarthritis[J].  Lasers Med Sci, 2020,35(4):823-832.

[34] Lai Yingjia, Yan Mingyue, Fan Jingqi, et al. Exploring the medication pattern of Chinese medicine in treating constipation in Parkinson's disease based on the Chinese medicine inheritance assistance platform[J]. New Chinese Medicine and Clinical Pharmacology, 2022,33(09):1277-1282.

[35] Zhang Yuan. Clinical observation of abdominal gua sha with pointers in the treatment of qi constipation[J]. Guangming Traditional Chinese Medicine, 2019,34(23):3631-3633.

[36] LI Ting, MIN Sufang. Progress in the diagnosis and treatment of chronic constipation[J]. Journal of Practical Cardiovascular and Pulmonary Vascular Disease, 2014,22(05):157-159.

[37] TANG Zhaoliang SONG Xiaoge WANG Ningxin ZHANG Fuqing CHEN Quanzhu. Study on the mechanism of activating blood circulation and removing blood stasis by moxibustion[J]. Journal of Anhui College of Traditional Chinese Medicine, 2004(02):24-28. 

[38] Chen Qiong. Clinical study of moxibustion at Shenque acupoint for the treatment of constipation in heart failure with Yang deficiency[J]. Journal of Practical Chinese Medicine, 2019,35(02):220-221.