Welcome to Francis Academic Press

The Frontiers of Society, Science and Technology, 2021, 3(7); doi: 10.25236/FSST.2021.030702.

Research on the treatment of the elderly with Alzheimer disease in virtual reality puzzle games


Ying Wu1,2, Wooksang Chang1

Corresponding Author:
Wooksang Chang

1Graduate School of Advanced Imaging Science, Multimedia and Film, Chung-Ang University, 06974, Korea

2Qingdao University of Science and Technology, 266061, China


Objective: To analyze the impact of educational games on the rehabilitation of older people with Alzheimer’s disease. Methods: According to the simple neuropsychiatric inventory (NPI), 60 older people with Alzheimer’s disease who received treatment in this study from April 2020 to May 2021 were selected as the research subjects [1]. The most presented data was recorded. The paired sample analysis method divided them into a control group (30 people) and an experimental group (30 people). The control group was given conventional medication only, and the experimental group was given puzzle game therapy. After the experiment, the mental state and cognitive function of the two groups of older people were compared. Results: 1) The experimental group changed significantly on the NPI questionnaire. 2) The indicators of the experimental group are better than those of the control group. The condition of the control group tends to worsen, and the experimental group’s condition tends to get better. Conclusion: Virtual reality puzzle games can improve the mental state and cognitive function of patients with Alzheimer’s disease to a certain extent and positively affect the rehabilitation of the elderly with Alzheimer’s disease [2].


Virtual reality puzzle games, Alzheimer disease, Treatment research

Cite This Paper

Ying Wu, Wooksang Chang. Research on the treatment of the elderly with Alzheimer disease in virtual reality puzzle games. The Frontiers of Society, Science and Technology (2021) Vol. 3, Issue 7: 5-8. https://doi.org/10.25236/FSST.2021.030702.


[1] Reitz, Christiane, Carol Brayne, and Richard Mayeux. (2011) Epidemiology of Alzheimer disease.” Nature Reviews Neurology, 137-152.

[2] MarcHofmann, AlexanderRösler, and WolframSchwarz. (2003) Interactive computer-training as a therapeutic tool in Alzheimer’s disease. Comprehensive Psychiatry, vol. 44, no. 3, 213-219.

[3] Cohen Manfield J, W erner P. (1997) Management of verbally disruptive behaviors in the nursing home.” J GeYOhtol}l Biol Sci Med, 6,52.

[4] Marilyn S. Albert, Steven T. DeKosky, and Dennis Dickson. (2011) The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement, vol. 7, 270–279.

[5] Goldsilver PM et al . (1990) Am JAlcheimers Dis Other Demen. 2, 16.

[6] Jane Bates, Jonathan Boote. (2004) Psycho-social intervention for people with a milder dementing illness: A systematic review.” JAdv Murs, 6, 45. 

[7] Peter T. Nelson. (2011) Elizabeth Head, and Frederick A. Schmitt, Alzheimer’s disease is not “brain aging”: Neuropathological, genetic, and epidemiological human studies. Acta Neuropathologica, vol.121, 5, 571-587.

[8] Jiska Cohen Mansfield. (2005) Non pharmacological interventions for persons with dementi a.” Alcheimer’s Care Quarterly, 6.

[9] Yamaguchi, H., Maki, Y., and Takahashi, K.. (2011) Rehabilitation for dementia using enjoyable video-sports games. Int. Psychogeriatr, 23, 674–676. 

[10] McKhann G, Drachman D et al. (1984) Clinical diagnosis of Alzheimer’s disease:R eport of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease.” Nenurology, 34.

[11] Jules C. Weiss. (1984) Creative Arts Therapy for Various Elder Populations, Activities. Adaptation and Aging, 5, 25-44.

[12] Beaulac J, Westmacott R, and Walker JR. (2016) The Mobilizing Minds Research Group Primary Care Provider Views About Usefulness and Dissemination of a Web-Based Depression Treatment Information Decision Aid. J Med Internet Res, vol. 18, 6, 153.

[13] Sokolov, Arseny A, and Collignon. (2020) Serious video games and virtual reality for prevention and neurorehabilitation of cognitive decline because of aging and neurodegeneration. Current Opinion in Neurology, vol. 33, 2, 239-248.