Welcome to Francis Academic Press

International Journal of Frontiers in Medicine, 2022, 4(2); doi: 10.25236/IJFM.2022.040204.

Scientific Research and Application of Flow Cytometry and Single Cell Analysis


Min Xu

Corresponding Author:
Min Xu

SMU Central Laboratory, Southern Medical University, Guangzhou, China


It is widely used in the clinical practice of small-scale biological separation (fctomet) and other biological separation methods, such as single row flow (FCM). Traditional research is carried out at the multi-cell level, which will lose a lot of heterogeneous information. Single cell technology can reveal the heterogeneity between cells and further explore the essence and law of life activities. It is widely used in the research of tumor cells, tumor networks and tumor stem cells. At the same time, it can help people better understand their occurrence, development and metastasis. Single cell technology has developed rapidly and made many innovative progress in the field of biology. Fully understanding the current development trend of flow cytometry and single cell technology can promote the development of immunology, developmental biology, neurobiology, cancer and other fields.


Flow Cytometry, Single Cell Analysis Technology, Combined Application

Cite This Paper

Min Xu. Scientific Research and Application of Flow Cytometry and Single Cell Analysis. International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 2: 16-20. https://doi.org/10.25236/IJFM.2022.040204.


[1] Meng Qingnan, Li Xiaoying, Xiong Xuelian Single cell transcriptome technology and its application in adipose tissue research . International Journal of Endocrinology and metabolism, 2022,42 (01): 27-31

[2] Peng Juqin, Ren Junguo, Gao Zhuye Application of single cell transcriptome sequencing technology in the study of cardiac protective mechanism of traditional Chinese medicine after myocardial infarction  Chinese Journal of experimental prescriptions, 2022,28 (05): 242-249

[3] Zhao Lei Transcriptome and epigenetic analysis of circulating tumor cells based on single cell technology . East China Normal University, 2021

[4] Xiong Heli, Sha Xi, Liu Shaona, Xiang Decai, Zhang Bin, Zhao Zhiyong Application of single cell transcriptome sequencing technology in animals [J / OL] Biotechnology Bulletin: 1-8 [2022-03-07].

[5] Cai Lin, Gong Qiuyuan, Wang Wei, Tian Hengli The latest progress of single cell sequencing analysis technology in the study of phenotypic heterogeneity of microglia . Chinese Journal of Neurosurgery, 2021,7 (03): 156-160

[6] Xiao Lei Xin Hongyi, a long-term teaching assistant professor of Shanghai Jiaotong University: the integration of information science and biomedicine promotes the application of single cell testing technology . China Hi tech, 2021 (11): 19-20

[7] Feng Chao Study on microenvironment heterogeneity of liver cancer and susceptibility of gastric tissue to new crown based on single cell transcriptome . Academy of Military Sciences, 2021

[8] Liu Jian Study on heterogeneity and related genes of cervical malignant tumors based on single cell transcriptome sequencing . Jilin University, 2021

[9] Wu Zihan Application of imaging flow cytometry in algae research . Shenzhen University, 2019

[10] Liu Dejing Screening, optimization and preliminary application of nucleic acid aptamers for marine pathogen Vibrio vulnificus . Second Military Medical University, 2017

[11] Sun Shaojun Study on the diagnostic value of urine dry chemical analysis and flow cytometry in urinary tract infection . Suzhou University, 2016

[12] Kang Zhihong Application of flow cytometry in clinical examination . Seeking medical advice (second half of the month), 2012,10 (11): 861-862

[13] Liu Guangda A new in vivo flow cytometry method for real-time monitoring of tumor cells in circulatory system . Fudan University, 2011

[14] Sha Wei, Sha Li, Xia Yiping, Guo Weina On flow cytometry in clinical medical examination . Chinese and foreign medical, 2011,30 (12): 186

[15] Li Jun, Hao Hongjun, Gao Feng, Huang Yining Clinical application prospect of flow cytometry in detecting T lymphocyte subsets in cerebrospinal fluid . Chinese Journal of neuroimmunology and neurology, 2011,18 (02): 129-131

[16] Julie Flow cytometry promotes the rapid development of life science. Science and technology daily, 2010-01-28 (010)